52144-91-9

Basic information

• Product Name: Ethanone, 1-[3,5-bis(phenylmethoxy)phenyl]-2-diazo-
• CAS NO: 52144-91-9
• Molecular Formula: C22H18N2O3
• Molecular Weight: 358.397
• Mol File: 52144-91-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[3,5-bis(phenylmethoxy)phenyl]-2-diazo-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[3,5-bis(phenylmethoxy)phenyl]-2-diazo-(52144-91-9)
• EPA Substance Registry System: Ethanone, 1-[3,5-bis(phenylmethoxy)phenyl]-2-diazo-(52144-91-9)

Safety Data

• Hazardous Substances Data: 52144-91-9(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 28917-44-4 3,5-dibenzyloxylbenzoyl chloride 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 100-44-7 benzyl chloride 
• 58605-10-0 methyl 3,5-bis(benzyloxy)benzoate 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 50513-72-9 (3,5-di-benzyloxy)benzoic acid benzyl ester 
• 28917-43-3 3,5-dibenzyloxybenzoic acid 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 186581-53-3 diazomethane 

Downstream Products

• 65857-84-3 8,10-bis(benzyloxy)-3-methoxy-1-methylbenzoxanthen-6,11,12-trione 
• 79762-39-3 1,3-diacetoxy-6,8-bis(benzyloxy)naphthalene 
• 65857-78-5 methyl 2-acetyl-3,5-bis(benzyloxy)phenylacetate 
• 79762-36-0 5,7-dibenzylflaviolin 
• 71741-18-9 6,8-Bis-benzyloxy-naphthalene-1,3-diol 
• 33390-21-5 bikaverin 
• 71741-20-3 1,3-bis(benzyloxy)-5-(2-benzyloxy-4-methoxy-6-methylbenzoyl)-8-(2-benzyloxy-4-methoxy-6-methylbenzoyloxy)-6-hydroxynaphthalene 
• 71741-23-6 1-acetoxy-6,8-bis(benzyloxy)-3-(2-benzyloxy-4-methoxy-6-methylbenzoyloxy)naphthalene 
• 71741-19-0 1,3-bis(benzyloxy)-6-(2-benzyloxy-4-methoxy-6-methylbenzoyloxy)-8-hydroxynaphthalene 
• 65857-81-0 1,3-bis(benzyloxy)-7-(2-benzyloxy-4-methoxy-6-methylbenzoyl)-6-(2-benzyloxy-4-methoxy-6-methylbenzoyloxy)-8-hydroxynaphthalene 
• 65857-80-9 1,3-bis(benzyloxy)-6,8-bis-(2-benzyloxy-4-methoxy-6-methylbenzoyloxy)naphthalene 
• 33390-22-6 norbikaverin 
• 65857-85-4 1,3-bis(benzyloxy)-10-methoxy-8-methylbenzoxanthen-5,6,7-trione 
• 65857-82-1 1,3-bis(benzyloxy)-6-(2-benzyloxy-4-methoxy-6-methylbenzoyloxy)-10-methoxy-8-methylbenzoxanthen-7-one 

Relevant articles and documents

A facile preparation of α-aryl carboxylic acid via one-flow arndt-eistert synthesis

An efficient, one-flow Arndt-Eistert synthesis was demonstrated. A sequence of acid chloride formation-nucleophilic acyl substitution-Wolff rearrangement-nucleophilic addition was performed in a microflow system without isolating any intermediates, which

A urinary metabolite of Δ1-tetrahydrocannabinol. The first synthesis of 4''-hydroxy-Δ1-tetrahydrocannabinol-7-oic acid labelled with deuterium

The first synthesis of 4''-hydroxy-Δ1-THC-7-oic acid, one of the three major metabolites of Δ1-THC identified in human urine is discussed. Methyl 4-(3,5-dihydroxyphenyl)butanoate (8) was prepared from 3,5-dihydroxybenzoic acid in an overall yield of 15%. 8 was condensed with a terpene synthon (9) under acidic conditions followed by hydrolysis and conversion of the 4''-carboxylic acid function to the corresponding methyl ketone using methyllithium. Reduction with NaBH4 afforded the secondary alcohol in the side-chain. Acetylation and removal of the 1,3-dithiane masking group gave the aldehyde in C-7-position which was further oxidized using NaClO2 followed by deacetylation to give the desired metabolite 14. The same procedure may be used for the synthesis of unlabelled 4''-hydroxy-Δ1-THC-7-oic acid.

Orally active bronchospasmolytic compounds and their preparation

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