52157-57-0

Basic information

• Product Name: 2-CHLOROMETHYL-5-METHYLFURAN
• CAS NO: 52157-57-0
• Molecular Formula: C6H7ClO
• Molecular Weight: 130.574
• Mol File: 52157-57-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-CHLOROMETHYL-5-METHYLFURAN (CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLOROMETHYL-5-METHYLFURAN (52157-57-0)
• EPA Substance Registry System: 2-CHLOROMETHYL-5-METHYLFURAN (52157-57-0)

Safety Data

• Safety Statements: A storage hazard. It may explode spontaneously at room temperature. Less stable than 2-chloromethylfuran. When heated to decomposition it emits toxic fumes of Clsup xmlns="">−/sup>. See also a target="_blank" href="lom/card_sa.tes?href=content/sax0006/sdp05337.xml&view=print">CHLORINATED HYDROCARBONS, AROMATIC/a>.
• HazardClass: 3
• Hazardous Substances Data: 52157-57-0(Hazardous Substances Data)

Upstream product

• 3857-25-8 2-hydroxymethyl-5-methylfuran 

Downstream Products

• 1451001-21-0 2-methyl-5-((1-phenylprop-2-ynyloxy)methyl)furan 
• 1235527-71-5 1-((5-methylfuran-2-yl)methyl)-4-p-tolyl-1H-1,2,3-triazole 
• 1235527-63-5 1-((5-methylfuran-2-yl)methyl)-4-phenyl-1H-1,2,3-triazole 
• 72360-04-4 (5-methyl-[2]furyl)-acetic acid 
• 18091-23-1 2-(methoxymethyl)-5-methylfuran 

Relevant articles and documents

-

-

Pd-catalyzed reaction of aryl halides and propargyl furylmethyl ethers: A novel pathway to functionalized dihydroisobenzofurans

An interesting sequential reaction involving Sonogashira coupling, propargyl-allenyl isomerization, intramolecular [4 + 2] cycloaddition, and bridged oxa-ring opening has been realized, providing a facile method for the synthesis of functionalized dihydroisobenzofurans from easily accessible starting materials with a decent diastereoselectivity.