52179-74-5Relevant articles and documents
Exploring the influence of steric hindrance and electronic nature of substituents in the supramolecular arrangements of 5-(substituted phenyl)-2-formylpyrroles
Figueira, Cludia A.,Lopes, Patrcia S.,Gomes, Clara S. B.,Veiros, Lus F.,Gomes, Pedro T.
, p. 6406 - 6419 (2015)
A family of 5-(substituted phenyl)-2-formylpyrrole compounds, exhibiting different electronic and steric features at the phenyl ring, was synthesised through the formylation reaction of the corresponding 2-(substituted phenyl)pyrrole precursors, using Vil
2,4-Imidazolinedione heterocyclic derivative, and preparation method and use thereof
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Paragraph 0123; 0126; 0127, (2017/07/01)
The invention belongs to the field of chemical medicines, and concretely relates to a 2,4-imidazolinedione heterocyclic derivative, and a preparation method and a use thereof. The structure of the 2,4-imidazolinedione heterocyclic derivative is represented by formula I. The invention also provides the preparation method and the use of the 2,4-imidazolinedione heterocyclic derivative. The 2,4-imidazolinedione heterocyclic derivative has a good inhibition effect on Pim-1 protein kinase micro-molecules, and has important exploitation application prospect.
Direct synthesis of pyrroles via a silver-promoted three-component reaction involving unusual imidazole ring opening
Zeng, Jing,Bai, Yaguang,Cai, Shuting,Ma, Jimei,Liu, Xue-Wei
supporting information; experimental part, p. 12855 - 12857 (2012/02/03)
A novel silver-promoted three-component reaction toward the synthesis of multifunctionalized pyrroles has been developed. This reaction involves an unusual imidazole ring decomposition, presumably via 1,5-isomerization and subsequent hydrolysis.
