521944-15-0

Basic information

• Product Name: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-OL
• Synonyms: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-OL;(8-syn)-3-Benzyl-3-azabicyclo[3.2.1]octan-8-ol;(8-syn);endo-3-benzyl-3-azabicyclo[3.2.1]octan-8-ol;(1R,5S)-3-benzyl-3-azabicyclo[3.2.1]octan-8-ol
• CAS NO: 521944-15-0
• Molecular Formula: C₁₄H₁₉NO
• Molecular Weight: 217.31
• Mol File: 521944-15-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-OL(521944-15-0)
• EPA Substance Registry System: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-OL(521944-15-0)

Safety Data

• Hazardous Substances Data: 521944-15-0(Hazardous Substances Data)

Usage

General Description

3-Benzyl-3-azabicyclo[3.2.1]octan-8-ol is a chemical compound with a complex molecular structure that includes a benzyl group and an azabicyclic ring system. It is classified as a bicyclic organic compound and is commonly used as a chemical intermediate and building block in the synthesis of various pharmaceutical drugs and natural products. Its unique structure and functional groups make it a valuable starting material for the preparation of diverse chemical compounds. Additionally, its potential biological activity and pharmacological properties make it an important target for medicinal chemistry and drug discovery research.

Upstream product

• 83507-33-9 3-benzyl-3-aza-bicyclo[3.2.1]octan-8-one 

Downstream Products

• 521944-35-4 N-benzyl-3-azabicyclo[3.2.1]octane-8α-yl trifluoromethanesulfonate 
• 522608-86-2 rac-(1R,5S,8S)-3-benzyl-3-azabicyclo[3.2.1]octan-8-ol 
• 1147553-19-2 C₂₅H₂₈N₄O₂ 

Relevant articles and documents

PROCESS FOR PRODUCTION OF CIS-3-SUBSTITUTED-3- AZABICYCLO[3.2.1]OCTAN-8-OL DERIVATIVE

There are provided, according to the present invention, a method for producing a cis-3-substituted-3-azabicyclo[3.2.1]octan-8-ol derivative, the method characterized in that a trans-3-substituted-3-azabicyclo[3.2.1]octan-8-ol derivative or a mixture of the trans- and cis-3-substituted-3-azabicyclo[3.2.1]octan-8-ol derivatives is isomerized in the presence of an aluminum compound represented by a formula Al(OR1)3 (wherein R1 represents a hydrocarbon group in which a carbon atom having an oxygen atom bonded thereto is a secondary carbon atom). In the process, a ketone compound may be further added, in addition to the aluminum compound.

BICYCLIC HETEROCYCLE DERIVATIVES AND METHODS OF USE THEREOF

The present invention relates to Bicyclic Heterocycle Derivatives, compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR119 in a patient.