522-06-5 Usage
General Description
Flindersiamine is a natural indole alkaloid derived from the Australian native plant Flindersia. It has been found to possess neuroprotective, anti-inflammatory, and anticancer properties. Studies have shown that flindersiamine has the ability to inhibit the growth of cancer cells by inducing apoptosis and causing cell cycle arrest. It also exerts its neuroprotective effects by modulating the release of neurotransmitters and protecting against oxidative stress and inflammation in the brain. These properties make flindersiamine a promising candidate for the development of pharmaceutical drugs for the treatment of cancer and neurodegenerative diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 522-06-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 2 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 522-06:
(5*5)+(4*2)+(3*2)+(2*0)+(1*6)=45
45 % 10 = 5
So 522-06-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H11NO5/c1-16-11-7-3-4-18-14(7)15-10-8(11)5-9-12(13(10)17-2)20-6-19-9/h3-5H,6H2,1-2H3
522-06-5Relevant articles and documents
Isolation and Identification of Three New Phenolic Furoquinoline Alkaloids from Teclea verdoorniana Exell and Mendonca (Rutaceae)
Ayafor, Johnson Foyere,Okogun, Joseph I.
, p. 909 - 916 (2007/10/02)
Separation of the stem bark extracts of Teclea verdoorniana Exell and Mendonca (Rutaceae) yielded three new phenolic furoquinoline alkaloids, 8-hydroxy-5-(3-methylbut-2-enyl)-6,7-methylenedioxydictamnine (tecleaverdoornine) (1), 8-hydroxy-5-(3-hydroxy-3-methylbutyl)-6,7-methylenedioxydictamnine (tecleaverdine) (7), and 8-hydroxy-6,7-methylenedioxy-dictamnine (tecleine) (8), along with known alkaloids flindersiamine and kokusaginine.The pentacyclic triterpene lupeol was also isolated in large quantities.The application of ethanolic hydrochloric acid as a selective 4-O-demethylating reagent for dictamnine-type alkaloids is discussed.
