52200-22-3 Usage
General Description
2-[(Dimethylamino)methylene]-3-oxo-3-(2-thienyl)propanenitrile is a chemical compound with the molecular formula C11H12N2OS. It is a yellow solid at room temperature and is used in the synthesis and production of pharmaceuticals and agrochemicals. This chemical is known for its ability to inhibit the growth of cancer cells, making it a potential candidate for anti-cancer drugs. It also exhibits anti-inflammatory and antioxidant properties, making it a versatile compound with potential applications in the treatment of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 52200-22-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,2,0 and 0 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 52200-22:
(7*5)+(6*2)+(5*2)+(4*0)+(3*0)+(2*2)+(1*2)=63
63 % 10 = 3
So 52200-22-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H10N2OS/c1-12(2)7-8(6-11)10(13)9-4-3-5-14-9/h3-5,7H,1-2H3/b8-7+
52200-22-3Relevant articles and documents
Studies with functionally substituted enamines: Synthesis of 2-aroyl-3-dimethylamino-2-propenenitrile and their reactivity toward nitrogen nucleophiles
Al-Qalaf, Fawzia,Abdelkhalik, Mervat Mohammed,Al-Enezi, Amal,Al-Ajmi, Johara Rashed
, p. 145 - 156 (2008/09/20)
A facile and efficient synthesis of 2-substituted 3-dimethylamino-2-propenenitrile 4a-c is described. Reaction of 4a-c with hydrazine hydrate afforded 3-substituted-1H-4-pyrazole carbonitrile 9a-c. Compounds 4a-c reacted with 5-methyl-1H-pyrazol-3-amine to give 7-substituted pyrazolo[1,5-a]pyrimidine-6-carbonitrile 12a-c and 2-substituted 5-aminopyrazolo[1,5-a]pyrimidine 16a,b, and with 1H-benzo[d]imidazol-2-amine to give 3-substituted 2-aminobenzo[4,5]imidazo[1,2-a]pyrimidine 19a,b and 4-substituted benzo[4,5]imidazo[1,2-a]pyrimidine 3-carbonitrile 21c. The structures of compounds obtained were deduced based on 1HNMR, HMBC-15N and NOE difference experiments.
