52267-50-2

Basic information

• Product Name: Butanoic acid, 2-diazo-3-oxo-, phenylmethyl ester
• CAS NO: 52267-50-2
• Molecular Formula: C11H10N2O3
• Molecular Weight: 218.212
• Mol File: 52267-50-2.mol
• Article Data: 32

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 2-diazo-3-oxo-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-diazo-3-oxo-, phenylmethyl ester(52267-50-2)
• EPA Substance Registry System: Butanoic acid, 2-diazo-3-oxo-, phenylmethyl ester(52267-50-2)

Safety Data

• Hazardous Substances Data: 52267-50-2(Hazardous Substances Data)

Upstream product

• 2684-62-0 diazoacetone 
• 124-38-9 carbon dioxide 
• 100-39-0 benzyl bromide 
• 941-55-9 4-toluenesulfonyl azide 
• 5396-89-4 benzyl acetoacetate 
• 13407-52-8 2-naphthalenesulphonyl azide 
• 100-51-6 benzyl alcohol 

Downstream Products

• 79975-81-8 Benzyl α-diazoacetoacetate trimethylsilyl enol ether 
• 1159410-95-3 benzyl 1,2-dihydro-3-methyl-1-oxoisoquinoline-4-carboxylate 
• 1423076-82-7 benzyl 2-methyl-1H-indole-3-carboxylate 
• 93552-78-4 benzyl 2,3-dioxobutanoate 
• 1423716-66-8 benzyl 5-propyl-1H-pyrazole-3-carboxylate 
• 1423716-56-6 benzyl 4,5,6,7-tetrahydro-1H-indazole-3-carboxylate 
• 943542-93-6 benzyl α-D-diazoacetate 

Relevant articles and documents

Catalytic Ring Expansion of Activated Heteroarenes Enabled by Regioselective Dearomatization

Catalytic ring expansion of activated heteroarenes through 1,4-dearomative addition of diazoacetates was established for the construction of various fused azepines by an elaborate control of the reaction kinetics at each step. The use of a silver catalyst was essential to drive the overall reaction for generating the desired seven-membered azepines. Because of the excellent substrate scope and selectivity, the developed methodology presents an innovative approach for the synthesis of multifused azepines, which are biologically relevant molecules.

Ruthenium(II)-Catalyzed Ortho-C-H Alkylation of Naphthylamines with Diazo Compounds for Synthesis of 2,2-Disubstituted π-Extended 3-Oxindoles in Water

Ruthenium(II)-catalyzed ortho-C-H alkylation of naphthylamines with diazo compounds for the synthesis of 2,2-disubstituted π-extended 3-oxindoles has been developed. The method represents the first example of C-H alkylation via carbenoid insertion in wate

Synthesis and use of a cost-effective, aqueous soluble diazo transfer reagent – m-carboxybenzenesulfonyl azide

Herein, we report the preparation and use of m-carboxybenzenesulfonyl azide as a diazo transfer reagent. This compound is an inexpensive and potentially scalable alternative to many of the diazo transfer reagents currently available, most of which have hazards associated with their use. Its usefulness and suitability as a diazo transfer reagent was assessed on the basis of cost, safety and its effectiveness in diazo transfer to a variety of different substrates.