5227-53-2

Basic information

• Product Name: 1-ALLYL-2-(2-HYDROXYETHYL)THIOUREA
• Synonyms: 1-ALLYL-2-(2-HYDROXYETHYL)THIOUREA;Azocane-2-carboxylic acid;azepane-2-carboxylic acid(SALTDATA: FREE);Hexahydro-1H-azepine-2-carboxylic acid;Hexahydroazepine-2-carboxylic acid;NSC 86359;1H-Azepine-2-carboxylicacid, hexahydro-;1H-Azepine-2-carboxylicacid
• CAS NO: 5227-53-2
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.1836
• Mol File: 5227-53-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 208-209℃
• Boiling Point: 281℃
• Flash Point: 124℃
• Appearance: /
• Density: 1.080
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• PKA: 2.47±0.20(Predicted)
• CAS DataBase Reference: 1-ALLYL-2-(2-HYDROXYETHYL)THIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ALLYL-2-(2-HYDROXYETHYL)THIOUREA(5227-53-2)
• EPA Substance Registry System: 1-ALLYL-2-(2-HYDROXYETHYL)THIOUREA(5227-53-2)

Safety Data

• Hazardous Substances Data: 5227-53-2(Hazardous Substances Data)

Usage

General Description

1-ALLYL-2-(2-HYDROXYETHYL)THIOUREA, also known as AETU, is a chemical compound with the molecular formula C7H13N3OS. It is a thiourea derivative that is commonly used as an inhibitor in the polymerization of vinyl monomers. AETU acts as a chain transfer agent, helping to control the molecular weight and branching of the resulting polymers. It is also used as a stabilizer in the production of acrylonitrile butadiene styrene (ABS) resins and as an additive in rubber and plastic manufacturing. In addition, AETU has applications in the field of medicine, where it is used as a radical scavenger and antioxidant. Its unique structure and properties make AETU a valuable and versatile compound in various industrial and scientific fields.

Upstream product

• 502-42-1 cycloheptanone 
• 673-66-5 7-amino-heptanoic acid lactam 
• 2158-31-8 cycloheptanone oxime 
• 32566-60-2 3-chlorohexahydroazocin-2(1H)-one 
• 1340116-86-0 aza-cycloheptane-7-carboxylic acid tert-butyl ester 
• 26228-96-6 3,3-dichlorohexahydroazocin-2(1H)-one 

Downstream Products

• 869307-76-6 N-benzyloxycarbonyl-(2S)-aminobutyryl-(2R/S)-perhydroazepinecarboxylic acid 
• 869307-77-7 N-benzyloxycarbonyl-(2S)-aminobutyryl-(2R/S)-perhydroazepinecarboxylic acid n-butylamide 
• 5228-33-1 methyl azepane-2-carboxylate 
• 1034708-26-3 (R)-1-(tert-butoxycarbonyl)-azepane-2-carboxylic acid 
• 1034708-26-3 1-(tert-butoxycarbonyl)-azepane-2-carboxylic acid 
• 155905-76-3 (2S)-1-(tert-butoxycarbonyl)-2-azepanecarboxylic acid 
• 66865-37-0 (S)-perhydro-2-azepinecarboxylic acid 

Relevant articles and documents

Polybasic nitrogen heterocyclic non-natural chiral amino acid and synthesis method thereof

The invention relates to a polybasic nitrogen heterocyclic non-natural chiral amino acid and a synthesis method thereof. The amino acid can be applied to molecule building for antibiotic synthesis. According to the synthesis method, 2-aminodiethyl malonate and halogenated alkanes carry out substitution reactions, cyclization reactions, and decarboxylation reactions, and the reaction products are split to obtain the polybasic nitrogen heterocyclic non-natural chiral amino acid. The provided novel synthesis method has the advantages of simple synthesis route, low cost, convenient operation, andeasiness for commercial production, the chiral purity of obtained products is high, and the application prospect is good.

Inhibitors of tripeptidyl peptidase II. 3. Derivation of butabindide by successive structure optimizations leading to a potential general approach to designing exopeptidase inhibitors

The cholecystokinin-8 (CCK-8)-inactivating peptidase is a serine peptidase that has been shown to be a membrane-bound isoform of tripeptidyl peptidase II (EC 3.4.14.10). It cleaves the neurotransmitter CCK-8 sulfate at the Met-Gly bond to give Asp-Tyr(SO