52284-17-0

Basic information

• Product Name: Benzene, 1,1'-(1,2-ethynediyl)bis[2,5-dimethyl-
• CAS NO: 52284-17-0
• Molecular Formula: C18H18
• Molecular Weight: 234.341
• Mol File: 52284-17-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-(1,2-ethynediyl)bis[2,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(1,2-ethynediyl)bis[2,5-dimethyl-(52284-17-0)
• EPA Substance Registry System: Benzene, 1,1'-(1,2-ethynediyl)bis[2,5-dimethyl-(52284-17-0)

Safety Data

• Hazardous Substances Data: 52284-17-0(Hazardous Substances Data)

Upstream product

• 95-72-7 2-chloro-1,4-dimethyl-benzene 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 471-25-0 Propiolic acid 
• 553-94-6 4-bromo-m-xylene 
• 142-45-0 Acetylenedicarboxylic acid 
• 106-42-3 para-xylene 
• 1122-42-5 2-iodo-p-xylene 
• 4301-14-8 acetylenemagnesium bromide 
• 74-86-2 acetylene 
• 52033-79-1 2,3-Bis-(2,5-dimethyl-phenyl)-cycloprop-2-enone 

Relevant articles and documents

One-pot synthesis of unsymmetrical diarylacetylenes via Sonogashira/deacetonation/Sonogashira cross-coupling of two different aryl chlorides with 2-methyl-3-butyn-2-ol

With the assistance of PdCl2/X-Phos as the catalyst system, a green and efficient protocol for one-pot Sonogashira/Deacetonation/Sonogashira coupling reaction of two different aryl chlorides with 2-methyl-3-butyn-2-ol was developed, affording various unsymmetrical diarylacetylenes in mostly moderate to excellent yields. Note that the cheap and economically available aryl chlorides and 2-methyl-3-butyn-2-ol as the starting materials could be added to the catalyst system directly and simultaneously. Moreover, this tandem reaction could tolerate substrates bearing one or even two ortho-sterically hindered groups and was also applicable to the synthesis of symmetrical diarylacetylenes. In addition, the competitive reaction was performed and a possible mechanism was also proposed. This journal is the Partner Organisations 2014.

Synthesis of symmetrical diarylalkyne from palladium-catalyzed decarboxylative couplings of propiolic acid and aryl bromides under water

Symmetric diarylalkynes were obtained from the decarboxylative coupling reactions of aryl bromides and propiolic acid in water solvent condition. In the presence of phase transfer surfactant C18H37N(CH 3)3Cl, the catalytic system of both Pd(PPh 3)2Cl2/dppb and Pd(TPPMS)2Cl 2/TPPMS afforded the desired coupled products in good yields.

Direct Synthesis of Terminal Alkynes via Pd-Catalyzed Cross Coupling of Aryl and Alkenyl Halides with Ethynylmetals Contang Zn, Mg, and Sn. Critical Comparison of Countercations

-