52372-86-8 Usage
Description
3-(N-ACETYL-L-CYSTEIN-S-YL) ACETAMINOPHEN, SODIUM SALT, also known as APAP-CYS, is a metabolite of acetaminophen (A161220) with a chemical structure characterized as an S-substituted N-acetyl-L-cysteine, where the S-substituent is 5-acetamido-2-hydroxyphenyl. It is a brownish-pink solid and has been implicated in nephrotoxicity.
Uses
Used in Pharmaceutical Industry:
3-(N-ACETYL-L-CYSTEIN-S-YL) ACETAMINOPHEN, SODIUM SALT is used as a metabolite for the study of acetaminophen's effects on the body, particularly in the context of nephrotoxicity. This understanding can aid in the development of safer analgesic and antipyretic drugs.
Used in Biological Research:
APAP-CYS is utilized as a key metabolite in biological studies, specifically in the field of urinary antihypertensive drug metabolite screening. This application employs molecular networking coupled to high-resolution mass spectrometry fragmentation, contributing to the advancement of drug metabolism research and the identification of potential drug interactions and side effects.
Used in Toxicology Studies:
In toxicology, 3-(N-ACETYL-L-CYSTEIN-S-YL) ACETAMINOPHEN, SODIUM SALT serves as an important biomarker for investigating the toxic effects of acetaminophen, a widely used analgesic and antipyretic drug. This helps in understanding the mechanisms of drug-induced toxicity and developing strategies to mitigate potential harm to patients.
Check Digit Verification of cas no
The CAS Registry Mumber 52372-86-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,3,7 and 2 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 52372-86:
(7*5)+(6*2)+(5*3)+(4*7)+(3*2)+(2*8)+(1*6)=118
118 % 10 = 8
So 52372-86-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H16N2O5S/c1-7(16)14-9-3-4-11(18)12(5-9)21-6-10(13(19)20)15-8(2)17/h3-5,10,18H,6H2,1-2H3,(H,14,16)(H,15,17)(H,19,20)/t10-/m0/s1