52372-95-9

Basic information

• Product Name: 1H-INDEN-1-AMINE, 2,3-DIHYDRO-5-METHOXY-
• Synonyms: 1H-INDEN-1-AMINE, 2,3-DIHYDRO-5-METHOXY-;5-Methoxy-2,3-dihydro-1H-inden-1-aMine;5-Methoxy-indan-1-ylamine
• CAS NO: 52372-95-9
• Molecular Formula: C10H13NO
• Molecular Weight: 163.22
• Mol File: 52372-95-9.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 279°Cat760mmHg
• Flash Point: 129.3°C
• Appearance: /
• Density: 1.087g/cm³
• Vapor Pressure: 0.00411mmHg at 25°C
• Refractive Index: 1.561
• Storage Temp.: 2-8°C
• PKA: 9.55±0.20(Predicted)
• CAS DataBase Reference: 1H-INDEN-1-AMINE, 2,3-DIHYDRO-5-METHOXY-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-INDEN-1-AMINE, 2,3-DIHYDRO-5-METHOXY-(52372-95-9)
• EPA Substance Registry System: 1H-INDEN-1-AMINE, 2,3-DIHYDRO-5-METHOXY-(52372-95-9)

Safety Data

• Hazardous Substances Data: 52372-95-9(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-5-methoxy 1H-inden-1-amine is a chemical compound belonging to the class of organic compounds known as indanes. Indanes are compounds containing an indane moiety, which is a cyclopentane fused to a benzene ring. This specific chemical has a methoxy group (-OCH3) attached to the fifth carbon of the indane ring and an amine group (-NH2) attached to the first carbon. The '2,3-Dihydro' part of its name refers to two hydrogen atoms being added across the 2nd and 3rd carbon atoms of the indane ring, suggesting it exists in a reduced state. The precise properties and uses of this chemical may vary depending on the context; however, in general, it is used for research purposes and organic synthesis.

InChI:InChI=1/C10H13NO/c1-12-8-3-4-9-7(6-8)2-5-10(9)11/h3-4,6,10H,2,5,11H2,1H3

Upstream product

• 90921-94-1 5-methoxy-1-indanone oxime 
• 64-19-7 acetic acid 
• 5111-70-6 5-methoxy-1-indanone 
• 121696-16-0 2,3-dihydro-5-methoxy-1H-inden-1-one O-methyloxime 
• 3470-49-3 5-hydroxy-2,3-dihydro-1H-indene-1-one 
• 3199-77-7 5-methoxy-2,3-dihydro-1H-inden-1-ol 

Relevant articles and documents

PERIPHERAL ALKYL AND ALKENYL CHAINS EXTENDED BENZENE DERIVATIVES AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME

The compounds represented by Formula (I), which are peripheral alkyl and alkenyl chains extended benzene derivatives, are useful as dual autotaxin (ATX) / histone deacetylase (HD AC) inhibitors. These compounds may be included in a pharmaceutical composition along with a pharmaceutically acceptable carrier, and be used in a therapeutically effective amount for prophylaxis or treatment of various diseases and disorders.

POTENT SMALL MOLECULE INHIBITORS OF AUTOPHAGY, AND METHODS OF USE THEREOF

Certain aspects of the invention relate to small molecule autophagy inhibitors, and their use for treatment and prevention of cancers and acute pancreatitis. Medicinal chemistry studies led to small molecular autophagy inhibitors with improved potency and selectivity.

(FUSED RING ARYLAMINO AND HETEROCYCLYLAMINO) PYRIMIDYNYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN TREATING PROLIFERATIVE DISEASES

Provided herein are (fused ring arylamino and heterocyclylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, e.g., a compound of Formula (I), and their pharmaceutical compositions, preparation, and use as agents or drugs for treating proliferative diseases.