52379-50-7

Basic information

• Product Name: Benzenecarboximidamide, N-(3-methylphenyl)-
• CAS NO: 52379-50-7
• Molecular Formula: C14H14N2
• Molecular Weight: 210.279
• Mol File: 52379-50-7.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: Benzenecarboximidamide, N-(3-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarboximidamide, N-(3-methylphenyl)-(52379-50-7)
• EPA Substance Registry System: Benzenecarboximidamide, N-(3-methylphenyl)-(52379-50-7)

Safety Data

• Hazardous Substances Data: 52379-50-7(Hazardous Substances Data)

Upstream product

• 100-47-0 benzonitrile 
• 108-44-1 1-amino-3-methylbenzene 
• 625-95-6 3-Iodotoluene 
• 1670-14-0 benzamidine monohydrochloride 
• 55-21-0 benzamide 
• 4113-72-8 1-azido-3-methylbenzene 
• 80949-07-1 N-(3-Methylphenyl)-N'-cyanbenzamidin 
• 17933-03-8 m-tolylboronic acid 
• 618-39-3 benzamidin 

Downstream Products

• 1325217-85-3 N-tert-butyl-4-amino-7-methyl-2-phenylquinazoline 
• 1325217-86-4 N-tert-butyl-4-amino-5-methyl-2-phenylquinazoline 
• 1423125-96-5 2,4-diphenyl-1-(m-tolyl)-1H-imidazole 
• 1446449-49-5 7-methyl-2-phenyl-3,4-dihydroquinazoline 
• 1446449-50-8 5-methyl-2-phenyl-3,4-dihydroquinazoline 
• 3659-77-6 4-methyl-2-phenyl-1H-benzimidazole 
• 2963-65-7 6-methyl-2-phenyl-1H-benzo[d]imidazole 
• 3659-77-6 7-methyl-2-phenyl-1H-benzo[d]imidazole 
• 2963-65-7 5-methyl-2-phenyl-1H-1,3-benzimidazole 
• 82636-06-4 6-Oxo-2-phenyl-1-m-tolyl-1,6-dihydro-pyrimidine-5-carboxylic acid ethyl ester 
• 89069-67-0 3-(3-methylphenyl)-2-phenyl-4(3H)-pyrimidinone 
• 82635-82-3 2-{[(N¹-m-Tolyl-benzimidoyl)-amino]-methylene}-malonic acid diethyl ester 
• 85616-19-9 6-methyl-1,3-diphenyl-1λ⁴,2,4-benzothiadiazine 
• 89069-83-0 3-(3-methylphenyl)-2,6-diphenyl-4(3H)-pyrimidinone 

Relevant articles and documents

Synthesis of aminoisoquinolines via Rh-catalyzed [4 + 2] annulation of benzamidamides with vinylene carbonate

A new strategy is developed for the synthesis of 1-aminoisoquinoline derivatives. This Rh(III)-catalyzed [4 + 2] annulation reaction employs benzamidines as efficient directing groups and the vinylene carbonate as an acetylene surrogate. Additionally, the reaction features broad substrate scopes and good yields, only producing carbonate anion as byproduct.

Transition-Metal-Free Synthesis of 1,2-diphenyl-1H-benzo[d] Imidazole Derivatives from N-phenylbenzimidamides and Cyclohexanones

A transition-metal-free strategy for the formation of 1,2-diphenyl-1H-benzo[d] imidazoles from N-phenylbenzimidamides and cyclohexanones is introduced. This is the first report on the direct synthesis of 1,2-diphenyl-1H-benzo[d] imidazoles from cyclohexanones and N-phenylbenzimidamides via iodine- promoted oxidative cyclization. Non-aromatic cyclohexanones were smoothly dehydrogenated, and acted as an aryl source using oxygen as a green oxidant. The catalytic use of iodine makes this method quite simple, more economical and convenient. Under optimized conditions, various substituted 1,2-diphenyl-1H-benzo[d] imidazoles were smoothly reacted, and the desired substituted imidazoles were generated with moderate to excellent yields. (Figure presented.).

Acid-catalyzed synthesis of imidazole derivatives via N-phenylbenzimidamides and sulfoxonium ylides cyclization

A straightforward method to synthesize imidazole derivatives from amidines and sulfoxonium ylides catalyzed by acids is reported in this study. Specifically, catalyzed by trifluoroacetic acid in DCE solvents can improve synthesis efficiency under metal-fr