52426-94-5

Basic information

• Product Name: Ethanediimidoyl dichloride, bis(4-methoxyphenyl)-
• CAS NO: 52426-94-5
• Molecular Formula: C16H14Cl2N2O2
• Molecular Weight: 337.205
• Mol File: 52426-94-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethanediimidoyl dichloride, bis(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanediimidoyl dichloride, bis(4-methoxyphenyl)-(52426-94-5)
• EPA Substance Registry System: Ethanediimidoyl dichloride, bis(4-methoxyphenyl)-(52426-94-5)

Safety Data

• Hazardous Substances Data: 52426-94-5(Hazardous Substances Data)

Upstream product

• 79-37-8 oxalyl dichloride 
• 104-94-9 4-methoxy-aniline 
• 10026-13-8 phosphorus pentachloride 
• 3299-63-6 N,N'-bis(4-methoxyphenyl) oxamide 
• 71-43-2 benzene 

Downstream Products

• 29082-66-4 2-diphenylamino-N,N'-bis-(4-methoxy-phenyl)-thiazole-4,5-diylidenediamine 
• 224641-09-2 C₂₃H₂₀N₄O₂ 
• 109735-65-1 (4-Methoxy-phenyl)-{2-[2-[4-(4-methoxy-phenylamino)-5-[(E)-4-methoxy-phenylimino]-5H-thiazol-(2E)-ylidene]-eth-(E)-ylidene]-5-[(E)-4-methoxy-phenylimino]-2,5-dihydro-thiazol-4-yl}-amine 
• 28989-41-5 N,N'-bis-(4-methoxy-phenyl)-2-(N-methyl-anilino)-thiazole-4,5-diylidenediamine 
• 75390-36-2 2,5-Di-p-anisidyl-3,4-di-p-anisidylimino-1,2,5-thiadiazolidin-S-oxid 
• 837363-84-5 (E)-3-(4-methoxyphenylamino)-1-(4-methoxyphenyl)-5-(6-methyl-2-oxocyclohex-1-ylidene)-2,5-dihydropyrrol-2-one 

Relevant articles and documents

A new synthesis of push-pull pyrroles, their oxidation to stable 3H-pyrroles and an unexpected anellation reaction

A. new synthesis of push-pull pyrroles of type 5 was developed starting from. bis(imidoyl chlorides) 1 and various iminodiacetic acid derivatives 3. The use of appropriate N-trifluoroacetyl residues as protecting/activating group proved to be the method, of choice for the straightforward, preparation of the 3,4-diarylamino-lH-pyrroles 5. When benzothiazole substructures are present in 2,5-position of heterocycles 5, a two-electron oxidation leads to 3H-pyrroles of type 6 in excellent yields. However, in the case of cyano or ester groups, a further oxidative process immediately led to the new 3H-pyrrolo[3,4-b] quinoxalines 7 via intramolecular ring anellation. 2009 Wiley-VCH Verlag GmbH & Co. KGaA,.

A new synthesis of bis-enaminones via acylation of ketones

A short and efficient synthesis for a series of 1,6-diaryl-3,4- diarylaminohexa-2,4-diene-1,6-diones was developed. Based on the acylation-prototropism sequence during the reaction of various aryl methyl ketones with bis-imidoyl chlorides, the products were isolated in good yields. Substituted acetophenones, acetylthiophene, 3-acetylpyridine, and acetylferrocene can be integrated into this reaction as ketone component. Similarly, α-tetralone can be transformed with bis-electrophiles into the corresponding bis-enaminones. Treatment of 2-acetylpyridine with N,N′-bis(4-tolyl)ethanebis(imidoyl) dichloride yielded not only the expected bis-enaminone, but also a new quinolizine derivative which was structurally characterized by single crystal X-ray analysis. Analogously, pinacolone and cyclopropyl methyl ketone can readily be converted into bis-enaminones. Monoimidoyl chlorides showed the same reactivity, providing derivatives in high yields. Georg Thieme Verlag Stuttgart.