5244-88-2

Basic information

• Product Name: (cyclobutylmethyl)benzene
• Synonyms: (Cyclobutylmethyl)benzene; benzene, (cyclobutylmethyl)-; Benzylcyclobutane
• CAS NO: 5244-88-2
• Molecular Formula: C₁₁H₁₄
• Molecular Weight: 146.2289
• Mol File: 5244-88-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 212.7°C at 760 mmHg
• Flash Point: 73.9°C
• Density: 0.979g/cm³
• Vapor Pressure: 0.248mmHg at 25°C
• Refractive Index: 1.55
• CAS DataBase Reference: (cyclobutylmethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (cyclobutylmethyl)benzene(5244-88-2)
• EPA Substance Registry System: (cyclobutylmethyl)benzene(5244-88-2)

Safety Data

• Hazardous Substances Data: 5244-88-2(Hazardous Substances Data)

Upstream product

• 5407-98-7 1-cyclobutyl-1-phenyl-methanone 
• 5244-84-8 (+/-)-cyclobutyl(phenyl)methanamine 
• 6668-40-2 cyclobutyl-phenyl ketone oxime 
• 5244-80-4 N,N-Dimethyl-α-phenyl-cyclobutyl-methylamin 
• 925-90-6 ethylmagnesium bromide 
• 678150-52-2 (Z)-3-phenyl-1-propenyl N,n-diisopropylcarbamate 
• 123245-94-3 (cyclobutylmethyl)magnesium bromide 

Downstream Products

• 82833-97-4 (1-bromo-1-phenylmethylene)cyclobutane 

Relevant articles and documents

A Close-to-Aromatize Approach for the Late-Stage Functionalization through Ring Closing Metathesis

An efficient approach for the synthesis of monosubstituted aromatic compounds relying on a ring-closing metathesis followed by spontaneous 1,2-elimination is presented. The efficiency for late-stage functionalization is highlighted in various solvents (up to 920 TON). This approach is compatible with strained cycles and other multiple bonds in the substrate.

Stereoselective synthesis of metalated cyclobutyl derivatives

Treatment of Z-vinyl carbamates with dicyclopentadienyl(diethyl)zirconium [Et2ZrCp2] leads to cyclobutyl-zirconocene derivatives in good yields and as a unique diastereoisomer. The reaction proceeds through a carbometalative ring-exp