52450-38-1 Usage
Description
AFMK, also known as N1-acetyl-N2-formyl-5-methoxykynuramine, is a melatonin metabolite that was first identified in rat brain. It is a light brown solid and possesses antioxidant and free radical scavenging activities in various experimental models. AFMK is also used as an index for measuring melatonin synthesis and metabolism in plasma.
Uses
Used in Pharmaceutical Industry:
AFMK is used as a pharmaceutical agent for its antioxidant and free radical scavenging properties. It helps in protecting cells from oxidative stress and damage, which can be beneficial in the treatment and prevention of various diseases associated with oxidative stress.
Used in Research and Diagnostics:
AFMK is used as a research tool and diagnostic marker for studying melatonin synthesis and metabolism. Its measurement in plasma can provide valuable insights into the circadian rhythms and sleep-wake cycles in mammals, including humans.
Used in Antioxidant Formulations:
AFMK can be used as an ingredient in antioxidant formulations, such as supplements and skincare products, due to its antioxidant properties. It can help protect the skin from environmental stressors and promote overall health and well-being.
Used in Sleep Aid Products:
Given its connection to melatonin synthesis and metabolism, AFMK can be used in the development of sleep aid products to help regulate sleep-wake cycles and improve sleep quality in individuals experiencing sleep disturbances or circadian rhythm disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 52450-38-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,4,5 and 0 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 52450-38:
(7*5)+(6*2)+(5*4)+(4*5)+(3*0)+(2*3)+(1*8)=101
101 % 10 = 1
So 52450-38-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H16N2O4/c1-9(17)14-6-5-13(18)11-7-10(19-2)3-4-12(11)15-8-16/h3-4,7-8H,5-6H2,1-2H3,(H,14,17)(H,15,16)
52450-38-1Relevant articles and documents
Radioimmunoassay of N-acetyl-N-formyl-5-methoxykynuramine (AFMK): A melatonin oxidative metabolite
Harthe, Catherine,Claudy, Daniele,Dechaud, Henri,Vivien-Roels, Berthe,Pevet, Paul,Claustrat, Bruno
, p. 1587 - 1597 (2003)
N-acetyl-N-formyl-5-methoxykynuramine (AFMK) is a melatonin metabolite identified in rat brain by Hirata et al. (The Journal of Biological Chemistry 249 (1974) 1311). Since no assay has been described for its routine measurement, we have developed and val
Oxidative coupling rearrangement product based on tryptamine skeleton and preparation method and application thereof
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Paragraph 0069-0077, (2021/09/01)
The invention discloses an oxidative coupling rearrangement product based on a tryptamine skeleton and a preparation method and application thereof, wherein a corresponding dicarbonyl compound is obtained by oxidizing a color amine compound by using sodiu
LONG-TERM MEMORY INDUCING AGENT
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, (2018/12/04)
[Problem] To provide a method for inducing a long-term memory in a subject need thereof. [Solution to problem] A method for inducing a long-term memory, comprising a step of administering a compound represented by Formula I below, a pharmaceutically accep
