524724-72-9

Basic information

• Product Name: 8-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE
• Synonyms: IFLAB-BB F1996-0001;8-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE;8-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE
• CAS NO: 524724-72-9
• Molecular Formula: C₁₅H₁₂N₂O
• Molecular Weight: 236.27
• Mol File: 524724-72-9.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE(524724-72-9)
• EPA Substance Registry System: 8-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE(524724-72-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 524724-72-9(Hazardous Substances Data)

Upstream product

• 1603-40-3 3-methylpyridin-2-ylamine 
• 70-11-1 α-bromoacetophenone 
• 885-89-2 8-methyl-2-phenylimidazo[1,2-a]pyridine 
• 68-12-2 N,N-dimethyl-formamide 
• 67-68-5 dimethyl sulfoxide 
• 104-55-2 3-phenyl-propenal 
• 93-61-8 N-methyl-N-phenylformamide 
• 110-18-9 N,N,N,N,-tetramethylethylenediamine 

Downstream Products

• 1423600-12-7 3-(8-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-1-p-tolylprop-2-en-1-one 
• 1423600-16-1 3-(8-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-1-(4-nitrophenyl)prop-2-en-1-one 
• 1423600-08-1 3-(8-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one 
• 1423598-95-1 8-methyl-2-phenyl-3-(3-p-tolyl-4,5-dihydro-1H-pyrazol-5-yl)imidazo[1,2-a]pyridine 
• 1423598-99-5 3-(3-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-5-yl)-8-methyl-2-phenyimidazo[1,2-a]pyridine 
• 1423599-03-4 8-methyl-2-phenyl-3-(3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)1H-imidazo[1,2-a]pyridine 
• 1423599-27-2 6-(4-fluorophenyl)-2-methoxy-4-(8-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)nicotinonitrile 
• 1423599-31-8 2-methoxy-4-(8-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-6-(4-nitrophenyl)nicotinonitrile 
• 1423599-35-2 2-methoxy-4-(8-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-6-p-tolylnicotinonitrile 
• 1423599-55-6 4-(8-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-6-(thiophen-2-yl)pyrimidin-2-amine 
• 1423599-59-0 4-(8-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-6-p-tolylpyrimidin-2-amine 
• 1423599-71-6 4-(8-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-6-p-tolyl-3,4-dihydropyrimidine-2(1H)-thione 
• 1435395-97-3 8-methyl-2-phenyl-imidazo[1,2-a]pyridine-3-carbaldehyde-O-prop-2-ynyl oxime 
• 1435396-38-5 8-methyl-2-phenylimidazo[1,2-a]pyridine-3-carbaldehyde-O-[1-(4-methylbenzyl)-1H-1,2,3-triazol-4-yl]methyl oxime 

Relevant articles and documents

Synthesis, Molecular Docking, BSA, and In Vitro Reactivation Study of Imidazopyridine Oximes Against Paraoxon Inhibited Acetylcholinesterase

Aim: To synthesize and evaluate the fused heterocyclic imidazo[1,2-a]pyridine based oxime as a reactivator against paraoxon inhibited acetylcholinesterase. Background: Organophosphorus compounds (OPs) include parathion, malathion, chlorpyrifos, monocrotop

Visible light induced tetramethylethylenediamine assisted formylation of imidazopyridines

A metal-free visible light induced C-3 formylation of imidazo[1,2-a]pyridine has been developed using tetramethylethylenediamine (TMEDA) as a one carbon source. An array of 3-formyl imidazo[1,2-a]pyridines with wide functionality are synthesized using rose bengal as a photosensitizer under ambient air.

A formyl Heteraromatic hydrocarbons the synthetic method of the compound of pharmaceutical intermediates

The invention relates to a method for synthesizing a formyl heterocyclic aromatic drug intermediate compound shown as a formula (I) in the specification. The method comprises the following step: enabling a compound of a formula (II) in the specification to react with a compound of a formula (III) in the specification in an organic solvent in the presence of a catalyst, an oxidant and reaction aids, thereby obtaining the compound of the formula (I), wherein R1, R2, R3 and R4 are respectively and independently selected from H, C1-C6 alkyl, C1-C6 alkoxy, phenyl or nitro. According to the method, the catalyst, oxidant, reaction aids and reaction substrate are selected and combined, so that formylation at a specific site is realized, and the method has high yield and has wide application prospects and potentials in the field of synthetic methods of drug intermediates.