52480-43-0

Basic information

• Product Name: 4,5-DIMETHYL-2-FURALDEHYDE
• Synonyms: 4,5-DIMETHYLFURFURAL;4,5-DIMETHYL-2-FURALDEHYD;4,5-DIMETHYL-2-FURALDEHYDE;4,5-DIMETHYL-2-FURANCARBOXALDEHYD;4,5-DIMETHYL-2-FURANCARBOXALDEHYDE;4,5-Dimethyl-2-furaldehyde,97%;4,5-Dimethyl-2-furancarboxaldehyde, GC 97%;4,5-Dimethyl-2-furancarboxaldehyde,97%
• CAS NO: 52480-43-0
• Molecular Formula: C₇H₈O₂
• Molecular Weight: 124.14
• EINECS: -0
• Mol File: 52480-43-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 98-100 °C12 mm Hg(lit.)
• Flash Point: 151 °F
• Appearance: /
• Density: 1.016 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.217mmHg at 25°C
• Refractive Index: n20/D 1.529(lit.)
• Storage Temp.: 0-6°C
• Sensitive: Air & Light Sensitive
• BRN: 107585
• CAS DataBase Reference: 4,5-DIMETHYL-2-FURALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DIMETHYL-2-FURALDEHYDE(52480-43-0)
• EPA Substance Registry System: 4,5-DIMETHYL-2-FURALDEHYDE(52480-43-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 24/25-37-26-23
• WGK Germany: 3
• Hazardous Substances Data: 52480-43-0(Hazardous Substances Data)

Usage

Description

4,5-DIMETHYL-2-FURALDEHYDE, also known as 2,6-Dimethyl-4-pyrrone, is a clear colorless to yellowish liquid that has been reported to undergo photochemical rearrangement. This rearrangement results in the formation of 4,5-DIMETHYL-2-FURALDEHYDE through a well-described mechanism. It is a versatile compound with various applications across different industries.

Uses

Used in Chemical Synthesis:
4,5-DIMETHYL-2-FURALDEHYDE is used as an intermediate in the synthesis of various organic compounds for [application reason] its ability to undergo photochemical rearrangement and serve as a building block for creating complex molecules.
Used in Flavor and Fragrance Industry:
4,5-DIMETHYL-2-FURALDEHYDE is used as a key component in the creation of unique fragrances and flavors for [application reason] its distinct chemical properties that contribute to the overall sensory experience of products.
Used in Pharmaceutical Industry:
4,5-DIMETHYL-2-FURALDEHYDE is used as a starting material for the development of new pharmaceutical compounds for [application reason] its potential to be modified and incorporated into drug molecules with desired therapeutic properties.
Used in Material Science:
4,5-DIMETHYL-2-FURALDEHYDE is used in the development of novel materials with specific properties for [application reason] its ability to be modified and combined with other compounds to create materials with tailored characteristics.
Used in Research and Development:
4,5-DIMETHYL-2-FURALDEHYDE is used as a research compound for [application reason] its unique photochemical properties and potential applications in various fields, making it an interesting subject for further study and development.

Synthesis Reference(s)

Journal of the American Chemical Society, 85, p. 1208, 1963 DOI: 10.1021/ja00891a046The Journal of Organic Chemistry, 49, p. 2512, 1984 DOI: 10.1021/jo00187a047

InChI:InChI=1/C7H8O2/c1-5-3-7(4-8)9-6(5)2/h3-4H,1-2H3

Upstream product

• 131044-40-1 2-(hydroxymethyl)-3-methyl-5-<(benzyloxy)methyl>furan 

Downstream Products

• 89639-83-8 4,5-dimethyl-furan-2-carboxylic acid 
• 129800-02-8 3-(4,5-dimethyl-2-furyl)propenoic acid 
• 134931-86-5 (1R,2R,4R)-5-Benzyloxy-1-(4,5-dimethyl-furan-2-yl)-1-hydroxy-2,4-dimethyl-pentan-3-one 
• 134860-57-4 (1S,2S,4R)-5-Benzyloxy-1-(4,5-dimethyl-furan-2-yl)-1-hydroxy-2,4-dimethyl-pentan-3-one 
• 10504-04-8 2,3,5-trimethylfuran 
• 904681-98-7 methyl (2Z)-2-{[(benzyloxy)carbonyl]amino}-3-(4,5-dimethyl-2-furyl)acrylate 
• 904682-03-7 methyl (2R)-(-)-2-benzyloxycarbonylamino-3-(4,5-dimethylfuran-2-yl)propanoate 
• 904682-19-5 (-)-benzyl (1R)-[2-(4,5-dimethyl-2-furyl)-1-(hydroxymethyl)ethyl]carbamate 
• 904682-23-1 (+)-benzyl (1R)-2-(4,5-diethyl-2-furyl)-1-({[tert-butyl(dimethyl)silyl]oxy}methyl)ethylcarbamate 
• 904682-31-1 (+)-4-bromo-N-{(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-[(4,5-dimethyl-2-furyl)methyl]ethyl}benzenesulfonamide 
• 904682-33-3 (+)-4-bromo-N-{(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-[(4,5-dimethyl-2-furyl)methyl]ethyl}-N-prop-2-ynylbenzenesulfonamide 
• 350691-82-6 N²-Phenyl-4,5-dimethylfuran-2-carboximidamide 
• 350692-13-6 N¹-Acetyl-N¹-(4,5-dimethyl-2-furyl)-N²-phenylurea 
• 155445-29-7 methyl 2,3-dimethyl-4H-furo[3,2-b]pyrrole-5-carboxylate 

Relevant articles and documents

Synthesis of Furans by Ag(I)-Promoted Cyclization of Allenyl Ketones and Aldehydes

A series of conjugated allenones (11b, 12b, 13c; 18a, 18b; 19b, 20b, AB and 27d) were prepared by Wittig rearrangement of (propargyloxy)acetic acids or stannanes followed by oxidation of the resultant allenylcarbinols.These all