52507-49-0

Basic information

• Product Name: 4-hydroxy-3-(2-propenyloxy)benzaldehyde
• Synonyms: 4-hydroxy-3-(2-propenyloxy)benzaldehyde
• CAS NO: 52507-49-0
• Molecular Weight: 178.188
• Mol File: 52507-49-0.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 4-hydroxy-3-(2-propenyloxy)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxy-3-(2-propenyloxy)benzaldehyde(52507-49-0)
• EPA Substance Registry System: 4-hydroxy-3-(2-propenyloxy)benzaldehyde(52507-49-0)

Safety Data

• Hazardous Substances Data: 52507-49-0(Hazardous Substances Data)

Upstream product

• 556-56-9 allyl iodid 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 106-95-6 allyl bromide 
• 875155-64-9 C₁₇H₂₄N₆O₅S 
• 18075-40-6 O-allylisovanillin 
• 621-59-0 isovanillin 
• 71186-67-9 3,4-diallyloxybenzaldehyde 
• 107-05-1 3-chloroprop-1-ene 
• 75-87-6 chloral 
• 1126-20-1 2-allyloxyphenol 

Downstream Products

• 18075-40-6 O-allylisovanillin 
• 1268721-33-0 2,7,12-tris-[2-[4-formyl-2-allyloxyphenoxy]ethoxy]-3,8,13-trimethoxy-10,15-dihydro-2H-tribenzo[a,d,g]cyclononene 
• 1190266-98-8 (E)-methyl 3-(3-(allyloxy)-4-hydroxyphenyl)-2-methylacrylate 
• 1338722-73-8 3-allyl-4-hydroxy-cinnamic acid 

Relevant articles and documents

Stereoselective synthesis of aryl 1,2-cis-furanosides and its application to the synthesis of the carbohydrate portion of antibiotic hygromycin A

An efficient methodology for the synthesis of aryl 1,2-cis-furanosidic linkages has been developed with 2-quinolinecarbonyl (Quin) group substituted furanose ethyl thioglycosides as glycosyl donors. The method permits a wide range of phenol acceptors to b

Synthesis of a Photo-Caged DOPA Derivative by Selective Alkylation of 3,4-Dihydroxybenzaldehyde

Natural and synthetic polymers containing the catechol moiety of noncoded amino acid 3,4-dihydroxyphenylalanine (DOPA) are capable of metal-coordination and adhesion under wet conditions. Masking the catechol subunit with a photo-cleavable group would provide an opportunity to design tunable adhesion properties that are especially important for biomaterial and biomedicine applications. Herein, we report the regioselective synthesis of a photo-caged DOPA bearing an ortho-nitrobenzyl (oNB) group that is capable of undergoing cleavage upon irradiation with UV light. We developed a selective synthetic route towards a 3-O-oNB alkylated DOPA regioisomer that can be readily incorporated into proteins by using a previously developed bio-expression platform. The synthesis is based on a regioselectivity switch in 3,4-dihydrozybenzaldehyde alkylation upon application of different equivalents of deprotonating base. The enantiomerically pure 3-O-oNB-DOPA was prepared on a gram scale and proved to be generally compatible with the solid-phase peptide synthesis conditions. We also demonstrate the general applicability of the developed synthetic strategy by providing the synthesis of 3-O-methyl-DOPA.

A Biomimetic Strategy to Access the Silybins: Total Synthesis of (-)-Isosilybin A

(Figure Presented). We report the first asymmetric, total synthesis of (-)-isosilybin A. A late-stage catalytic biomimetic cyclization of a highly functionalized chalcone is employed to form the characteristic benzopyranone ring. A robust and flexible app