52583-41-2Relevant articles and documents
Trichloroethanimidic acid esters
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, (2008/06/13)
New and more efficient chemical processes are provided for preparing (αS, 5S)-α-amino-3-chloro-2-isoxazoline-5-acetic acid (AT-125), (αS, 5S)-α-amino-3-bromo-2-isoxazoline-5-acetic acid (bromo AT-125) and the C-5 epimers thereof. The disclosed processes allow the above-mentioned antitumor agents to be produced in high yield and purity with substantially fewer steps than prior art chemical procedures.
A short, efficient total synthesis of (±) acivicin and (±) bromo-acivicin
Vyas,Chiang,Doyle
, p. 487 - 490 (2007/10/02)
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