52599-27-6 Usage
Description
N-(2-BROMOPHENYL)-N'-METHYLTHIOUREA, with the molecular formula C8H8BrN2S, is a white to off-white crystalline powder. It is a chemical compound that serves as a reagent in organic synthesis and a pharmaceutical intermediate. N-(2-BROMOPHENYL)-N'-METHYLTHIOUREA is recognized for its ability to inhibit the polymerization of tubulin, a protein that plays a crucial role in cell division. Its potential anti-tumor and anti-cancer properties have made it a significant subject of interest in medical research. Furthermore, it has demonstrated antifungal and antibacterial activities, suggesting its potential use in developing new antimicrobial agents.
Uses
Used in Pharmaceutical Industry:
N-(2-BROMOPHENYL)-N'-METHYLTHIOUREA is used as a pharmaceutical intermediate for its role in the synthesis of various medicinal compounds.
Used in Organic Synthesis:
In the field of organic synthesis, N-(2-BROMOPHENYL)-N'-METHYLTHIOUREA is utilized as a reagent, contributing to the creation of a wide range of organic compounds.
Used in Cancer Research:
N-(2-BROMOPHENYL)-N'-METHYLTHIOUREA is employed as a subject of study in cancer research due to its potential anti-tumor and anti-cancer properties, offering insights into new therapeutic approaches.
Used in Antimicrobial Development:
N-(2-BROMOPHENYL)-N'-METHYLTHIOUREA is used in the development of new antimicrobial agents, capitalizing on its demonstrated antifungal and antibacterial activities to combat various infections.
Check Digit Verification of cas no
The CAS Registry Mumber 52599-27-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,5,9 and 9 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 52599-27:
(7*5)+(6*2)+(5*5)+(4*9)+(3*9)+(2*2)+(1*7)=146
146 % 10 = 6
So 52599-27-6 is a valid CAS Registry Number.
52599-27-6Relevant articles and documents
Synthesis of 2-substituted-benzothiazoles by palladium-catalyzed intramolecular cyclization of o-bromophenylthioureas and o-bromophenylthioamides
Benedí, Carolina,Bravo, Fernando,Uriz, Pedro,Fernández, Elena,Claver, Carmen,Castillón, Sergio
, p. 6073 - 6077 (2007/10/03)
2-Amino-, and 2-alkyl-benzothiazoles have been efficiently prepared by palladium catalyzed cyclization of o-bromophenylthioureas and o-bromophenylthiamides. Results were best with the Pd2(dba)3/monophosphine catalytic system.
