52602-27-4

Basic information

• Product Name: 9-methyl-9H-carbazol-3-ol
• Synonyms: 9H-Carbazol-3-ol, 9-methyl-; 9-Methyl-9H-carbazol-3-ol
• CAS NO: 52602-27-4
• Molecular Formula: C₁₃H₁₁NO
• Molecular Weight: 197.2325
• Mol File: 52602-27-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 405.7°C at 760 mmHg
• Flash Point: 199.2°C
• Density: 1.2g/cm³
• Vapor Pressure: 3.66E-07mmHg at 25°C
• Refractive Index: 1.647
• CAS DataBase Reference: 9-methyl-9H-carbazol-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 9-methyl-9H-carbazol-3-ol(52602-27-4)
• EPA Substance Registry System: 9-methyl-9H-carbazol-3-ol(52602-27-4)

Safety Data

• Hazardous Substances Data: 52602-27-4(Hazardous Substances Data)

Upstream product

• 152404-99-4 3-methoxy-9-methyl-9H-carbazole 
• 21240-56-2 9-methyl-9H-carbazole-3-carbaldehyde 
• 108164-09-6 5-(1,3-dimethylindol-2-ylmethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 1484-12-4 N-methylcarbazole 
• 86-74-8 9H-carbazole 
• 18992-85-3 3-methoxycarbazole 
• 1592-95-6 3-bromo-9H-carbazole 

Downstream Products

• 355408-50-3 2,6-dihydro-6-methyl-2,2-diphenylpyrano[3,2-b]carbazole 

Relevant articles and documents

TEMPO-mediated late stage photochemical hydroxylation of biaryl sulfonium salts

The late stage photochemical hydroxylation of biaryl sulfonium salts was enabled with a TEMPO derivative as a simple oxygen source, in metal free conditions. The scope and mechanism of this exceptionally simple synthetic method, which constructs important arylated phenols from aromatic C-H bonds, are herein discussed.

REGIOSPECIFIC C-9 SUBSTITUTION OF ELLIPTICINE DERIVATIVES

6-Methylellipticine (6) undergoes acylation at the C(9)-position, under Friedel Crafts reaction conditions.The C(9)-formyl compound (8) rearranges to the corresponding hydroxy derivative (9) upon treatment with hydrogen peroxide, in methanol, in the presence of sulphuric acid.The two steps provide a convenient procedure for the specific C(9)-hydroxylation of the ellipticine template.

Flash Vacuum Pyrolysis of 5-(Indol-2- and -3-ylmethylene)-2,2-dimethyl-1,3-dioxane-4,6-diones

Flash vacuum pyrolysis of 5-(indol-2- and -3-ylmethylene)-2,2-dimethyl-1,3-dioxane-4,6-diones results in the initial formation of indolylmethyleneketenes, which generally either lose carbon monoxide to produce ethynylindoles or undergo -sigmatropic shifts, followed by electrocyclic rearrangements, to yield carbazolols or benzindol-5(1H)-one. 5-(Indol-2-ylmethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione and the 3-methylindol-2-yl derivative both yield 3H-pyrroloindol-3-ones via a -sigmatropic rearrangement of the initially formed ketene.