52603-88-0

Basic information

• Product Name: 4-(2'-Nitrophenyl)-1,4-dihydropyridine-2,3,5,6-tetracarboxylic acid tetraethyl ester
• Synonyms: 4-(2'-Nitrophenyl)-1,4-dihydropyridine-2,3,5,6-tetracarboxylic acid tetraethyl ester
• CAS NO: 52603-88-0
• Molecular Weight: 490.467
• Mol File: 52603-88-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(2'-Nitrophenyl)-1,4-dihydropyridine-2,3,5,6-tetracarboxylic acid tetraethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2'-Nitrophenyl)-1,4-dihydropyridine-2,3,5,6-tetracarboxylic acid tetraethyl ester(52603-88-0)
• EPA Substance Registry System: 4-(2'-Nitrophenyl)-1,4-dihydropyridine-2,3,5,6-tetracarboxylic acid tetraethyl ester(52603-88-0)

Safety Data

• Hazardous Substances Data: 52603-88-0(Hazardous Substances Data)

Upstream product

• 600160-23-4 3-ethoxycarbonyl-2-oxopropionaldehyde 
• 52604-04-3 imino-succinic acid diethyl ester 
• 552-89-6 2-nitro-benzaldehyde 

Relevant articles and documents

2,3,5,6-Tetracarboxy-1,4-dihydropyridine derivatives

1,4-Dihydropyridines bearing carboxy functions in the 3-, 5- and 6- or 2-, 3-, 5- and 6-positions and being substituted in the 4-position by phenyl, substituted phenyl, naphthyl, phenylalkyl or a heterocyclic group are antihypertensive agents and coronary vessel dilators. The compounds, of which 2-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5,6-tricarboxylic acid triethylester is a representative embodiment, are prepared through condensation of an enamine with an ylidene acid ester, the latter being separately prepared or prepared in situ.