52612-51-8

Basic information

• Product Name: (+)-(1'R,6'S)-4-(2',2',6'-trimethylcyclohexyl)butan-2-one
• Synonyms: (+)-(1'R,6'S)-4-(2',2',6'-trimethylcyclohexyl)butan-2-one
• CAS NO: 52612-51-8
• Molecular Weight: 196.333
• Mol File: 52612-51-8.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: (+)-(1'R,6'S)-4-(2',2',6'-trimethylcyclohexyl)butan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(1'R,6'S)-4-(2',2',6'-trimethylcyclohexyl)butan-2-one(52612-51-8)
• EPA Substance Registry System: (+)-(1'R,6'S)-4-(2',2',6'-trimethylcyclohexyl)butan-2-one(52612-51-8)

Safety Data

• Hazardous Substances Data: 52612-51-8(Hazardous Substances Data)

Upstream product

• 139406-49-8 (+)-(1R,6S)-2,2,6-trimethylcyclohexane-1-methanol 
• 79-77-6 (E)-β-ionone 
• 13720-37-1 dihydro-α-ionol 
• 127-41-3 alpha-ionone 
• 64-17-5 ethanol 
• 13155-64-1 cis-dihydroionone 
• 64-19-7 acetic acid 
• 163235-20-9 3,4-dehydro-β-ionone 
• 4361-23-3 cis-tetrahydroionol 
• 127-41-3 alpha-ionone 
• 79-77-6 4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one 
• 24190-33-8 (+)-(S)-dihydro-γ-ionone 
• 141-78-6 ethyl acetate 
• 909697-73-0 (+)-(4R,6S)-4-(acetyloxy)-γ-ionone 

Downstream Products

• 144-62-7 oxalic acid 
• 856256-98-9 2,4-dioxo-6-(2,2,6-trimethylcyclohexyl)-hexanoic acid ethyl ester 
• 847502-74-3 C₂₅H₃₄O₂ 
• 52209-27-5 (+/-)-methyl-[(Ξ)-1-methyl-3-(2,2,6c-trimethyl-cyclohex-r-yl)-propyl]-amine 
• 85874-14-2 3-methyl-5-(2,2,6-trimethyl-cyclohexyl)-pent-2-enal 
• 4361-23-3 cis-tetrahydroionol 

Relevant articles and documents

Chemoselective hydrogenation of the olefinic bonds using a palladium/magnesium-lanthanum mixed oxide catalyst

A palladium/magnesium-lanthanum mixed oxide catalyst is found to be an efficient heterogeneous catalyst for the chemoselective hydrogenation of olefinic double bonds in the presence of various functional groups. The catalyst was recovered by centrifugation and reused for several cycles with consistent activity and selectivity. Copyright

Layered double hydroxides supported nano palladium: An efficient catalyst for the chemoselective hydrogenation of olefinic bonds

Chemoselective hydrogenation of olefinic double bonds in the presence of various functional groups using layered double hydroxides supported nanopalladium (LDH-Pd0) catalyst is described. LDH-Pd0 was recovered quantitatively by simple filtration and reused several times with consistent activity and selectivity.

Synthesis, olfactory evaluation, and determination of the absolute configuration of the 3,4-didehydroionone stereoisomers

The synthesis of 3,4-didehydroionone isomers 4, (+)-6, and (-)-6 and of 3,4-didehydro-7,8-dihydroionone isomers 5, (+)-7, and (-)-7 was accomplished starting from commercially available racemic α-ionone (1). Their preparation of the racemic forms 4-7 was first achieved by mean of a number of chemo- and regioselective reactions (Schemes 1 and 2). The enantio- and diastereoselective lipase-mediated kinetic acetylation of 4-hydroxy-γ- ionone (10a/10b) provided 4-hydroxy-γ-ionone (+)-10a/(±)-10b and (+)-4-(acetyloxy)-γ-ionone ((+)12b) (Scheme 3). The latter compounds were used as starting materials to prepare the 3,4-didehydro-γ-ionones (+)- and (-)-6 and the 3,4-didehydro-7,8-dihydro-γ-ionones (+)- and (-)-7 in enantiomer-enriched form. The absolute configuration of (+)-12b was determine by chemical correlation with (+)-(6S)-γ-ionone ((+)-3) and with (-)-(6S)-α-ionone ((-)-1) therefore allowing to assign the (S)-configuration to (+)-6 and (+)-7. Olfactory evaluation of the above described 3,4-didehydroionone isomers shows a significant difference between the enantiomers and regioisomers both in fragrance feature and in detection threshold (Table).