52616-99-6

Basic information

• Product Name: L-Proline, 1-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, 1,1-dimethylethyl ester
• CAS NO: 52616-99-6
• Molecular Formula: C22H32N2O5
• Molecular Weight: 404.506
• Mol File: 52616-99-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Proline, 1-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Proline, 1-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, 1,1-dimethylethyl ester(52616-99-6)
• EPA Substance Registry System: L-Proline, 1-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, 1,1-dimethylethyl ester(52616-99-6)

Safety Data

• Hazardous Substances Data: 52616-99-6(Hazardous Substances Data)

Upstream product

• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 2812-46-6 proline tert-butyl ester 

Downstream Products

• 55757-64-7 Z-Phe-Val-Pro-OH 
• 82213-51-2 Z-Phe-Val-Pro-OBu^t 
• 47450-18-0 N-benzyloxycarbonyl-L-valyl-L-proline 

Relevant articles and documents

Amides in one pot from Carboxylic Acids and Amines via Sulfinylamides

An efficient method has been developed for the direct amidification of carboxylic acids via sulfinylamides preformed in situ by the reaction of pure amines with prop-2- ene-1-sulfinyl chloride. The method can be applied to aliphatic acids, including pivalic acid, aromatic acids, and primary and secondary amines. It is compatible with acids bearing unprotected alcohol, phenol, and ketone moieties and applicable to the synthesis of peptides. It does not induce their a-epimerization.