5267-50-5

Basic information

• Product Name: N-[(4-methylphenyl)(phenyl)methyl]acetamide
• Synonyms: N-[(4-methylphenyl)(phenyl)methyl]acetamide
• CAS NO: 5267-50-5
• Molecular Weight: 239.317
• Mol File: 5267-50-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: N-[(4-methylphenyl)(phenyl)methyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(4-methylphenyl)(phenyl)methyl]acetamide(5267-50-5)
• EPA Substance Registry System: N-[(4-methylphenyl)(phenyl)methyl]acetamide(5267-50-5)

Safety Data

• Hazardous Substances Data: 5267-50-5(Hazardous Substances Data)

Upstream product

• 620-83-7 1-methyl-4-(phenylmethyl)benzene 
• 75-05-8 acetonitrile 
• 1309582-76-0 N,N'-sulfonyl bis-[(4-fluorophenyl)(4-methylphenyl)methanamine] 
• 108-24-7 acetic anhydride 
• 1309582-70-4 N,N'-sulfonyl bis-[(4-methylphenyl)(phenyl)methylamine] 
• 24388-23-6 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole 
• 87100-32-1 2-[chloro(phenyl)methyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 867182-05-6 N-[phenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]acetamide 
• 106-38-7 para-bromotoluene 
• 867181-97-3 (+/-)-1-acetamido-1-phenylmethaneboronic acid 
• 55095-21-1 phenyl-p-tolylmethylamine 
• 75-36-5 acetyl chloride 
• 71-43-2 benzene 
• 117067-49-9 N-[1-benzotriazol-1-yl-1-(4-methylphenyl)methyl]acetamide 

Relevant articles and documents

Chemoselective formation of C–N bond in wet acetonitrile using amberlyst-15(H) as a recyclable catalyst

An economically efficient and environmentally benign protocol for the chemoselective one-pot synthesis of diversely N-substituted amides has been developed in good yield through the reaction of benzylic secondary alcohols as well as aliphatic tertiary alcohols and alkyl/aryl nitriles. Commercially available Amberlyst-15(H) has been utilized at 80 °C as an air-stable and reusable heterogeneous inexpensive solid acid catalyst without any anhydrous and inert environment. The attractive features of the present synthetic protocol are mild reaction conditions, short reaction time, excellent chemoselectivity, high atom economy and tolerance of various sensitive moieties.

Method for preparing amide from aryl methane derivative and nitrile

The invention provides a simple and efficient method for directly preparing an amide compound from an aryl methane derivative and nitrile. In the method, manganese triacetate dihydrate is used as a catalyst, and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone(DDQ) is used as an oxidizing agent. The method has the characteristics that raw materials are cheap and easy to obtain, the source of the nitrile is wide, reaction conditions are mild, the applicability is wide and the like. The method solves the problems that ceric ammonium nitrate (CAN) and a fluorine agent which are used by a method for directly synthesizing amide by using aryl methane and nitrile compounds are hard to treat, atomic economy is poor, the source of the nitrile is narrow and the like.

α-Amidobenzylation of aryl and alkenyl halides via palladium-catalyzed Suzuki-Miyaura coupling with α-(acylamino) benzylboronic esters

The Suzuki-Miyaura coupling of α-(acetylamino)benzylboronic esters with aryl and alkenyl halides has been achieved using a Pd/P(t-Bu)3 catalyst with KF and H2O in 1,4-dioxane, giving α-substituted benzylamines in high yields. Copyright