5272-85-5 Usage
General Description
3,5-Diphenyl-1H-pyrazol-4-aMine, also known as diphenylpyrazolamine, is an organic chemical compound with the molecular formula C17H14N4. It is a white to off-white crystalline powder that is used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. 3,5-Diphenyl-1H-pyrazol-4-aMine belongs to the pyrazole class of chemicals, which are known for their diverse biological activities and are commonly used in medicinal chemistry. 3,5-Diphenyl-1H-pyrazol-4-aMine has been studied for its potential anti-inflammatory and analgesic properties, and it is also used as a reagent for organic synthesis and as a building block for the production of other pyrazole derivatives. However, it is important to handle this compound with caution as it can be harmful if ingested or inhaled, and it may cause skin and eye irritation.
Check Digit Verification of cas no
The CAS Registry Mumber 5272-85-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,7 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5272-85:
(6*5)+(5*2)+(4*7)+(3*2)+(2*8)+(1*5)=95
95 % 10 = 5
So 5272-85-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H13N3/c16-13-14(11-7-3-1-4-8-11)17-18-15(13)12-9-5-2-6-10-12/h1-10H,16H2,(H,17,18)
5272-85-5Relevant articles and documents
The conversion of isothiazoles into pyrazoles using hydrazine
Ioannidou, Heraklidia A.,Koutentis, Panayiotis A.
experimental part, p. 7023 - 7037 (2009/12/06)
The conversion of isothiazoles into pyrazoles on treatment with hydrazine is investigated. The influence of various C-3, C-4 and C-5 isothiazole substituents and some limitations of this ring transformation are examined. When the isothiazole C-3 substituent is a good nucleofuge, 3-aminopyrazoles are obtained. However, when the 3-substituent is not a leaving group it is retained in the pyrazole product. Treatment of 4-bromo-3-chloro-5-phenylisothiazole 56 or 3-chloro-4,5-diphenylisothiazole 57 with anhydrous hydrazine at ca. 200 °C for a few minutes gives the corresponding 3-hydrazinoisothiazoles 61 and 64 respectively in high yields; the stability of these new hydrazines is investigated. 5,5′-Diphenyl-3,3′-biisothiazole-4,4′-dicarbonitrile 78 reacts with hydrazine to give 5,5′-diphenyl-3,3′-bi(1H-pyrazole)-4,4′-dicarbonitrile 79. Methylhydrazine reacts with 3-chloro-5-phenylisothiazole-4-carbonitrile 1 to give 3-(1-methylhydrazino)-5-phenylisothiazole-4-carbonitrile 83 and 3-amino-1-methyl-5-phenylpyrazole-4-carbonitrile 84. All products are fully characterised and rational mechanisms for the isothiazole into pyrazole transformation are proposed.
