52758-21-1

Basic information

• Product Name: Ethanone, 1-(4-cycloheptylphenyl)-
• CAS NO: 52758-21-1
• Molecular Formula: C15H20O
• Molecular Weight: 216.323
• Mol File: 52758-21-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(4-cycloheptylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-cycloheptylphenyl)-(52758-21-1)
• EPA Substance Registry System: Ethanone, 1-(4-cycloheptylphenyl)-(52758-21-1)

Safety Data

• Hazardous Substances Data: 52758-21-1(Hazardous Substances Data)

Upstream product

• 2404-35-5 cycloheptyl bromide 
• 99-90-1 para-bromoacetophenone 
• 291-64-5 cycloheptane 
• 98-86-2 acetophenone 
• 7140-24-1 7,8,9,10-tetrahydro-6H-benzo[b]cyclohepta[d]thiophene 
• 4401-18-7 phenylcycloheptane 
• 75-36-5 acetyl chloride 

Downstream Products

• 610781-38-9 ethyl 3-hydroxy-3-(4'-cycloheptylphenyl)-butanoate 
• 92728-72-8 4-Cycloheptylacetophenone oxime 
• 92697-88-6 (4-ethylphenyl)cycloheptane 

Relevant articles and documents

General C(sp2)-C(sp3) Cross-Electrophile Coupling Reactions Enabled by Overcharge Protection of Homogeneous Electrocatalysts

Cross-electrophile coupling (XEC) of alkyl and aryl halides promoted by electrochemistry represents an attractive alternative to conventional methods that require stoichiometric quantities of high-energy reductants. Most importantly, electroreduction can readily exceed the reducing potentials of chemical reductants to activate catalysts with improved reactivities and selectivities over conventional systems. This work details the mechanistically-driven development of an electrochemical methodology for XEC that utilizes redox-active shuttles developed by the energy-storage community to protect reactive coupling catalysts from overreduction. The resulting electrocatalytic system is practical, scalable, and broadly applicable to the reductive coupling of a wide range of aryl, heteroaryl, or vinyl bromides with primary or secondary alkyl bromides. The impact of overcharge protection as a strategy for electrosynthetic methodologies is underscored by the dramatic differences in yields from coupling reactions with added redox shuttles (generally >80%) and those without (generally 20%). In addition to excellent yields for a wide range of substrates, reactions protected from overreduction can be performed at high currents and on multigram scales.

Preparation method of 4-cycloalkylacetophenone derivatives

The invention discloses a preparation method of 4-cycloalkylacetophenone derivatives, and belongs to the technical field of organic compounds. A 2-substituted acetophenone derivative or a 3-substituted acetophenone derivative is used as an initiator, so raw materials are easy to obtain and have many kinds; and the 4-substituted cycloalkyl acetophenone derivatives obtained by using the method are various, can be directly used, and can also be used in other further reactions. The preparation method has the advantages of simplicity in reaction operation and post-treatment, high yield, and no generation of a large amount of metal salts, is a green method with high atom economy, and is suitable for large-scale production.

Synthesis of Certain Mesogenic Azomethines Derived from 4-Cycloalkylanilines and from 4-Cycloalkylbenzaldehydes

General procedures are described for the synthesis of members of five pairs of related homologous series of mesogenic azomethines differing in the mode of linkage of the CH=N group and containing a cycloalkyl group in a terminal position.