52768-23-7

Basic information

• Product Name: 1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL HYDROBROMIDE
• Synonyms: 1,2,3,4-TETRAHYDRO ISOQUINOLINE-6,7-DIOL HYDROBROMIDE;1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL HYDROBROMIDE;TIMTEC-BB SBB000855;1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL HYDROBROMIDE 98%;1,2,3,4-Tetrahydro-6,7-isoquinolinediol hydrobromide,98%;1,2,3,4-Tetrahydro-6,7-isoquinolinediol hydrobroMide, 98% 1GR;52768-23-7
• CAS NO: 52768-23-7
• Molecular Formula: BrH*C₉H₁₁NO₂
• Molecular Weight: 246.1
• Mol File: 52768-23-7.mol
• Article Data: 15

Chemical Properties

• Melting Point: 210 °C
• Boiling Point: 379.3 °C at 760 mmHg
• Flash Point: 202.8 °C
• Appearance: Beige to gray-green to brownish/Powder
• Vapor Pressure: 2.7E-06mmHg at 25°C
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL HYDROBROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL HYDROBROMIDE(52768-23-7)
• EPA Substance Registry System: 1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL HYDROBROMIDE(52768-23-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-51-22
• Safety Statements: 37/39-26
• Hazardous Substances Data: 52768-23-7(Hazardous Substances Data)

Usage

Chemical Properties

BEIGE TO BROWN POWDER

InChI:InChI=1/C9H11NO2.BrH/c11-8-3-6-1-2-10-5-7(6)4-9(8)12;/h3-4,10-12H,1-2,5H2;1H

Upstream product

• 2328-12-3 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline monohydrochloride 
• 1745-07-9 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 50-00-0 formaldehyd 
• 645-31-8 3-hydroxytyramine hydrobromide 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 

Downstream Products

• 639468-08-9 3-(6,7-dihydroxy-3,4-dihydro-1H-isoquinolin-2-yl)-1-phenylpropanone 
• 639468-12-5 2-(3-hydroxy-3-phenylpropyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diyl diacetate 
• 639468-15-8 2-[3-phenyl-3-(2-trifluoromethylphenoxy)propyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diyl acetate 

Relevant articles and documents

BROAD SPECTRUM ANTIVIRAL COMPOSITIONS AND METHODS

Novel thiazole- and isoquinoline- containing compounds are presented that are useful for treating and/or preventing broad-spectrum viral infections. Methods of treating and/or preventing broad-specturm viral infections are also presented. These compounds have shown inhibitio of HCMV, influenza viruses, Zika virus, BK Virus and RSV replication in cell-based assays.

Catechol reactivity: Synthesis of dopamine derivatives substituted at the 6-position

Dopamine is a ubiquitous neurotransmitter essential in the proper functioning of the human body. In addition to this critical role, the catecholamine core has shown utility as a scaffold for numerous drugs and in other applications, like metal detection and adhesive materials. Substituents at the 6-position of dopamine’s catechol core can modulate its stereoelectronic properties, the acidity of its phenolic hydroxyl groups, and the overall hydrophobicity of the molecule. Herein, we report the synthesis of a series of four novel dopamine analogues substituted at the 6-position of catechol core. The1H NMR chemical shift of the aromatic proton meta to the substituent correlated strongly with the Hammett σmconstant, confirming the electronic properties of substituents.

Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements

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