527759-06-4

Basic information

• Product Name: Acetamide, N-[3-(dimethylamino)phenyl]-N-methyl-
• CAS NO: 527759-06-4
• Molecular Formula: C11H16N2O
• Molecular Weight: 192.261
• Mol File: 527759-06-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[3-(dimethylamino)phenyl]-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[3-(dimethylamino)phenyl]-N-methyl-(527759-06-4)
• EPA Substance Registry System: Acetamide, N-[3-(dimethylamino)phenyl]-N-methyl-(527759-06-4)

Safety Data

• Hazardous Substances Data: 527759-06-4(Hazardous Substances Data)

Upstream product

• 2836-04-6 m-dimethylaminoaniline 
• 619-31-8 N,N-dimethyl-3-nitroaniline 
• 50-00-0 formaldehyd 
• 61679-27-4 N-(3-aminophenyl)-N-methyl-acetamide 
• 7474-95-5 N'-acetyl-N,N-dimethyl-m-phenylenediamine 
• 74-88-4 methyl iodide 

Downstream Products

• 84995-19-7 N¹,N¹,N³-trimethylbenzene-1,3-diamine 

Relevant articles and documents

Amide conformational switching induced by protonation of aromatic substituent

(Matrix presented) Introduction of an electron-withdrawing group on the aromatic ring of N-methylacetanilide decreased the ratio of the cis conformer, and the ratio correlates well with the Hammett σ values of the substituents. These steric properties can be applied to achieve amide conformational swiching by protonation at the aromatic substituent of 4-[bis(dimethylamino)]-N-methylacetanilide or N-[p-(dimethylamino)phenyl]-N-phenylacetamide.