5279-83-4

Basic information

• Product Name: Cyclopropanecarboxamide, N,N-dimethyl-2-phenyl-, trans-
• CAS NO: 5279-83-4
• Molecular Formula: C12H15NO
• Molecular Weight: 189.257
• Mol File: 5279-83-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Cyclopropanecarboxamide, N,N-dimethyl-2-phenyl-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxamide, N,N-dimethyl-2-phenyl-, trans-(5279-83-4)
• EPA Substance Registry System: Cyclopropanecarboxamide, N,N-dimethyl-2-phenyl-, trans-(5279-83-4)

Safety Data

• Hazardous Substances Data: 5279-83-4(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 62285-47-6 2-diazo-N,N-dimethyl-acetamide 
• 186581-53-3 diazomethane 
• 100-52-7 benzaldehyde 
• 23020-15-7 (1S,2S)-2-phenylcyclopropane-1-carboxylic acid 
• 124-40-3 dimethyl amine 
• 939-87-7 (1SR,2SR)-2-phenylcyclopropanecarbonyl chloride 

Downstream Products

• 110659-58-0 (1S,2S)-trans-1-(hydroxymethyl)-2-phenylcyclopropane 

Relevant articles and documents

Controlled Reduction of Carboxamides to Alcohols or Amines by Zinc Hydrides

New protocols for controlled reduction of carboxamides to either alcohols or amines were established using a combination of sodium hydride (NaH) and zinc halides (ZnX2). Use of a different halide on ZnX2 dictates the selectivity, wherein the NaH-ZnI2 system delivers alcohols and NaH-ZnCl2 gives amines. Extensive mechanistic studies by experimental and theoretical approaches imply that polymeric zinc hydride (ZnH2)∞ is responsible for alcohol formation, whereas dimeric zinc chloride hydride (H?Zn?Cl)2 is the key species for the production of amines.

ENHANCEMENT OF STEREOSELECTIVITY IN CATALYTIC CYCLOPROPANATION REACTIONS

Significat enhancement of trans(anti) stereoselectivity is achieved in rhodium(II) acetamide catalyzed cyclopropanation reactions of 2,3,4-trimethyl-3-pentyl diazoacetate (ODA) and diazoacetamides.