52815-81-3

Basic information

• Product Name: Carbamic acid, [(1S)-1-methyl-2-[(4-nitrophenyl)amino]-2-oxoethyl]-, 1,1-dimethylethyl ester
• CAS NO: 52815-81-3
• Molecular Formula: C14H19N3O5
• Molecular Weight: 309.322
• Mol File: 52815-81-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S)-1-methyl-2-[(4-nitrophenyl)amino]-2-oxoethyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S)-1-methyl-2-[(4-nitrophenyl)amino]-2-oxoethyl]-, 1,1-dimethylethyl ester(52815-81-3)
• EPA Substance Registry System: Carbamic acid, [(1S)-1-methyl-2-[(4-nitrophenyl)amino]-2-oxoethyl]-, 1,1-dimethylethyl ester(52815-81-3)

Safety Data

• Hazardous Substances Data: 52815-81-3(Hazardous Substances Data)

Upstream product

• 15761-38-3 L-N-Boc-Ala 
• 100-01-6 4-nitro-aniline 

Downstream Products

• 1668-13-9 L-alanine-p-nitroanilide 

Relevant articles and documents

Proline-based dipeptides with two amide units as organocatalyst for the asymmetric aldol reaction of cyclohexanone with aldehydes

A series of proline-based dipeptide organocatalysts with two amide units (1-16) have been developed and evaluated in the direct catalytic asymmetric aldol reactions of aldehydes with cyclohexanone. These catalysts showed good solubility in organic solvents compared with their corresponding carboxyl terminal dipeptides. The robust amide bond formation allowed structural modifications and fine tuning of catalyst properties by varying the stereo and electronic effects of the terminal amide to affect the ability of hydrogen bonding formation between the catalysts and the substrates. The reactions proceeded smoothly in high yields (up to 99%), enantioselectivities (up to 98% ee) and anti-diastereoselectivities (up to 99:1) in the presence of bifunctional organocatalyst 4 under the optimal reaction conditions.

Peptidic analogues of the insect juvenile hormone containing urethan type protecting groups

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