52820-13-0

Basic information

• Product Name: 3-Amino-2-hydroxybenzyl alcohol
• Synonyms: 3-Amino-2-hydroxybenzyl alcohol;Benzenemethanol, 3-amino-4-hydroxy-;2-Amino-4-(hydroxymethyl)phenol
• CAS NO: 52820-13-0
• Molecular Formula: C₇H₉NO₂
• Molecular Weight: 139.15
• Mol File: 52820-13-0.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Amino-2-hydroxybenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-2-hydroxybenzyl alcohol(52820-13-0)
• EPA Substance Registry System: 3-Amino-2-hydroxybenzyl alcohol(52820-13-0)

Safety Data

• Hazardous Substances Data: 52820-13-0(Hazardous Substances Data)

Upstream product

• 41833-13-0 4-hydroxymethyl-2-nitrophenol 
• 3011-34-5 4-hydroxy-3-nitrobenzaldehyde 

Downstream Products

• 62267-63-4 michigazone 
• 915160-96-2 (3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-methanol 
• 120629-64-3 <(S)-(benzyloxycarbonyl)-L-valyl>-N-<1-<<5-<<(tert-butyldimethylsilyl)oxy>methyl>benzoxazol-2-yl>carbonyl>-2-methylpropyl>-L-prolinamide 

Relevant articles and documents

A molecular approach to rationally constructing specific fluorogenic substrates for the detection of acetylcholinesterase activity in live cells, mice brains and tissues

Acetylcholinesterase (AChE) is an extremely critical hydrolase tightly associated with neurological diseases. Currently, developing specific substrates for imaging AChE activity still remains a great challenge due to the interference from butyrylcholinesterase (BChE) and carboxylesterase (CE). Herein, we propose an approach to designing specific substrates for AChE detection by combining dimethylcarbamate choline with a self-immolative scaffold. The representative P10 can effectively eliminate the interference from CE and BChE. The high specificity of P10 has been proved via imaging AChE activity in cells. Moreover, P10 can also be used to successfully map AChE activity in different regions of a normal mouse brain, which may provide important data for AChE evaluation in clinical studies. Such a rational and effective approach can also provide a solid basis for designing probes with different properties to study AChE in biosystems and another way to design specific substrates for other enzymes. This journal is

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Saccharide sensing molecules having enhanced fluorescent properties

The present invention provides formulae for fluorescent compounds that have a number of properties which make them uniquely suited for use in sensors of analytes such as saccharides. The advantageous fluorescent properties include favorable excitation wavelengths, emission wavelengths, fluorescence lifetimes, and photostability. Additional advantageous properties include enhanced aqueous solubility, as well as temperature and pH sensitivity. The compound comprises an aryl or a substituted phenyl botonic acid that acts as a substrate recognition component, a fluorescence switch component, and a fluorophore. Fluorescent compounds are described that are excited at wavelengths greater than 400 nm and emit at wavelengths greater than 450 nm, which is advantageous for optical transmission through skin. The fluorophore is typically selected from transition metal-ligand complexes and thiazine, oxazine, oxazone, or oxazine-one as well as anthracene compounds. The fluorescent compound can be immobilized in a glucose permeable biocompatible polymer matrix that is implantable below the skin.