52838-73-0

Basic information

• Product Name: L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-, diphenylmethyl ester
• CAS NO: 52838-73-0
• Molecular Formula: C21H25NO5
• Molecular Weight: 371.433
• Mol File: 52838-73-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-, diphenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-, diphenylmethyl ester(52838-73-0)
• EPA Substance Registry System: L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-, diphenylmethyl ester(52838-73-0)

Safety Data

• Hazardous Substances Data: 52838-73-0(Hazardous Substances Data)

Upstream product

• 56-45-1 L-serin 
• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 908093-98-1 diazodiphenylmethane 
• 3262-72-4 (S)-N-(tert-butoxycarbonyl)serine 
• 5350-57-2 benzophenone hydrazone 

Downstream Products

• 1226873-20-6 (R)-1-hexadecyl-2-(5'-hexenyl)-sn-glycero-3-phospho-N-boc-L-serine-benzhydryl ester 
• 470459-03-1 (R)-3-Bromo-2-[(naphthalene-2-sulfonyl)-((E)-3-phenyl-allyl)-amino]-propionic acid benzhydryl ester 
• 470458-92-5 (S)-3-Hydroxy-2-[(naphthalene-2-sulfonyl)-((E)-3-phenyl-allyl)-amino]-propionic acid benzhydryl ester 
• 470459-04-2 (R)-3-Bromo-2-[(4-nitro-benzenesulfonyl)-((E)-3-phenyl-allyl)-amino]-propionic acid benzhydryl ester 
• 470458-93-6 (S)-3-Hydroxy-2-[(4-nitro-benzenesulfonyl)-((E)-3-phenyl-allyl)-amino]-propionic acid benzhydryl ester 
• 470459-01-9 (R)-3-Bromo-2-[((E)-3-phenyl-allyl)-(toluene-4-sulfonyl)-amino]-propionic acid benzhydryl ester 
• 470458-90-3 (S)-3-Hydroxy-2-[((E)-3-phenyl-allyl)-(toluene-4-sulfonyl)-amino]-propionic acid benzhydryl ester 
• 470459-05-3 (R)-2-[Allyl-(naphthalene-2-sulfonyl)-amino]-3-bromo-propionic acid benzhydryl ester 
• 470458-94-7 (S)-2-[Allyl-(naphthalene-2-sulfonyl)-amino]-3-hydroxy-propionic acid benzhydryl ester 
• 470458-88-9 (S)-2-[Allyl-(toluene-4-sulfonyl)-amino]-3-hydroxy-propionic acid benzhydryl ester 
• 470458-99-2 (R)-2-[Allyl-(toluene-4-sulfonyl)-amino]-3-bromo-propionic acid benzhydryl ester 

Relevant articles and documents

Synthesis of 1-O-alkyl-2-O-methyl-glycerophospholipids with potential antitumor activity

Some synthetic alkyl-lysophospholipid analogs have been described as a new class of immunopotentiating and antitumor agents. Among them, 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine has been reported to possess the highest antitumor activity. A new method for the synthesis of this compound and of the ethanolamine- and serine-containing analog is reported. 1-Alkyl-2-methyl-rac-glycerol, prepared from 1,2-isopropylidene-glycerol, is phosphorylated and the intermediate is condensed either with N-t-BOC-protected ethanolamine or with N-t-BOC-protected serine benzhydryl ester. The choline-derivative is obtained by methylation with CH3I of the ethanolamine derivative. The same synthetic sequence has been used also for synthesizing compounds unsaturated at the fatty alkyl chain in position 1 of the glycerol moiety. Preliminary observation are reported on the selective cytolytic action of the compounds on a tumor cell line.

7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof

This invention relates to novel 7-acylamino-3-vinyl-cephalosporanic acid derivatives and pharmaceutically acceptable salts thereof, of high antimicrobial activity.