52855-19-3

Basic information

• Product Name: 2-Aminomethyl-4-chloro-3,5,6-trimethyl-phenol; hydrochloride
• CAS NO: 52855-19-3
• Molecular Weight: 236.141
• Mol File: 52855-19-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Aminomethyl-4-chloro-3,5,6-trimethyl-phenol; hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Aminomethyl-4-chloro-3,5,6-trimethyl-phenol; hydrochloride(52855-19-3)
• EPA Substance Registry System: 2-Aminomethyl-4-chloro-3,5,6-trimethyl-phenol; hydrochloride(52855-19-3)

Safety Data

• Hazardous Substances Data: 52855-19-3(Hazardous Substances Data)

Upstream product

• 6627-94-7 4-chloro-2,3,5-trimethylphenol 
• 52780-50-4 2-Chloro-N-(3-chloro-6-hydroxy-2,4,5-trimethyl-benzyl)-acetamide 

Relevant articles and documents

2-(Aminomethyl)phenols, a new class of saluretic agents. I. Effect of nuclear substitution

A series of 2-(aminomethyl)phenols was synthesized and tested in rats and dogs for saluretic and diuretic activity. A number of these compounds exhibit a high order of activity on iv or po administration. The most active compounds belong to a subseries of 4-alkyl-6-halo derivatives of which 2,2(aminomethyl)-4-(1,1-dimethylethyl)-6-iodophenyl, is the most active. Compound 2 also possesses significant antihypertensive activity, an adjunctive pharmacological parameter which distinguishes 2 from the other compounds prepared in this series. In addition, 2 displays both topical saluretic and antiinflammatory activities.