528576-23-0

Basic information

• Product Name: N-[3-(methylsulfanyl)phenyl]benzenesulfonamide
• Synonyms: N-[3-(methylsulfanyl)phenyl]benzenesulfonamide
• CAS NO: 528576-23-0
• Molecular Formula: C₁₃H₁₃NO₂S₂
• Molecular Weight: 279.37782
• Mol File: 528576-23-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-[3-(methylsulfanyl)phenyl]benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-(methylsulfanyl)phenyl]benzenesulfonamide(528576-23-0)
• EPA Substance Registry System: N-[3-(methylsulfanyl)phenyl]benzenesulfonamide(528576-23-0)

Safety Data

• Hazardous Substances Data: 528576-23-0(Hazardous Substances Data)

Upstream product

• 98-10-2 benzenesulfonamide 
• 33733-73-2 3-bromo-1-(methylthio)benzene 

Relevant articles and documents

Sulfonamidation of Aryl and Heteroaryl Halides through Photosensitized Nickel Catalysis

Herein we report a highly efficient method for nickel-catalyzed C?N bond formation between sulfonamides and aryl electrophiles. This technology provides generic access to a broad range of N-aryl and N-heteroaryl sulfonamide motifs, which are widely represented in drug discovery. Initial mechanistic studies suggest an energy-transfer mechanism wherein C?N bond reductive elimination occurs from a triplet excited NiII complex. Late-stage sulfonamidation in the synthesis of a pharmacologically relevant structure is also demonstrated.