52868-69-6

Basic information

• Product Name: 5-amino-2-(methylsulfanyl)-1,3-thiazole-4-carboxamide
• Synonyms: 5-amino-2-(methylsulfanyl)-1,3-thiazole-4-carboxamide
• CAS NO: 52868-69-6
• Molecular Formula: C5H7N3OS2
• Molecular Weight: 189.25858
• Mol File: 52868-69-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 422.3°Cat760mmHg
• Flash Point: 209.2°C
• Appearance: /
• Density: 1.52g/cm³
• Vapor Pressure: 2.45E-07mmHg at 25°C
• Refractive Index: 1.69
• CAS DataBase Reference: 5-amino-2-(methylsulfanyl)-1,3-thiazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-2-(methylsulfanyl)-1,3-thiazole-4-carboxamide(52868-69-6)
• EPA Substance Registry System: 5-amino-2-(methylsulfanyl)-1,3-thiazole-4-carboxamide(52868-69-6)

Safety Data

• Hazardous Substances Data: 52868-69-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H7N3OS2/c1-10-5-8-2(3(6)9)4(7)11-5/h7H2,1H3,(H2,6,9)

Upstream product

• 52868-63-0 5-amino-2-thioxo-2,3-dihydro-thiazole-4-carboxylic acid amide 
• 77-78-1 dimethyl sulfate 
• 52868-63-0 5-amino-2-mercaptothiazole-4-carboxamide 

Downstream Products

• 52948-43-3 2-Methylmercaptothiazolo<5,4-d>-pyrimidin-7(6H)-on 
• 73109-38-3 5-amino-2-(methylthio)thiazole-4-carbonitrile 
• 73109-39-4 2-Methylmercaptothiazolo<5,4-d>-pyrimidin-5,7(4H,6H)-dithion 
• 5539-46-8 5-aminothiazole-4-carboxamide 

Relevant articles and documents

Novel bi-cyclic or tri-cyclic heterocyclic compound

The present invention provides novel bi-cyclic or tri-cyclic compound represented by formula (I) or pharmaceutical acceptable salt thereof, [wherein, ring A is an aromatic group which may be substituted, one of X1 and X2 is a carbon atom, and another is a nitrogen atom, X3 is a nitrogen atom or CR2, X4 is a nitrogen atom or CR3, X5 is a sulfur atom or -CH=CH-, Z1 is an oxygen atom, -C(R6)(R7)-, -NH-, -C(R6)(R7)-NH-, -NH-C(R6)(R7)-, -C(R6)(R7)-O-, -O-C(R6)(R7)- or a single bone, one of Z2 and Z3 is CH and another one is a nitrogen atom, or both are nitrogen atoms, the other symbols are same as those defined in the specification.]

Synthesis of novel thiazolo[5,4-d]pyrimidines

2-Methylsulphanyl-5-aminothiazole-4-carboxamide 1 has been used as a convenient precursor for the synthesis of new thiazolo[4,5-e][l,2,4-triazolo][4, 3-c]pyrimidines 5 and the corresponding tetrazolo analogue 7. A mesoionic isomer 8 seems to exist along w