528852-00-8Relevant articles and documents
Electrophilic amination of racemic and non-racemic allenyltitaniums. One-pot synthesis of α-hydrazinoalkynes from propargylic alcohol derivatives
An, Duk Keun,Hirakawa, Koichiro,Okamoto, Sentaro,Sato, Fumie
, p. 3737 - 3740 (1999)
Successive treatment of propargylic carbonates or phosphates with a Ti(O-i-Pr)4/2i-PrMgCl reagent and dialkyl azodicarboxylates gave α- hydrazinoalkynes in good yields. The reaction, which proceeded with up to 86% chiral transfer, thus has opened up a new route to optically active α- hydrazinoalkynes from the optically active propargylic compounds.