529-00-0 Usage
Description
N-(b-Hydroxytrimethylen)morpholinium chloride, also known as N-Morpholino-N-(b-hydroxyisopropyl)ammonium chloride, is an organic compound with a quaternary ammonium structure. It is characterized by its hydroxy and amine groups, which enable interactions with various substrates and applications across different industries.
Uses
Used in Chemical Synthesis:
N-(b-Hydroxytrimethylen)morpholinium chloride is used as an intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical and chemical industries. Its unique structure allows it to participate in a range of reactions, facilitating the creation of complex molecules and contributing to the development of new drugs and materials.
Used in Pharmaceutical Applications:
In the pharmaceutical industry, N-(b-Hydroxytrimethylen)morpholinium chloride is used as a building block for the development of new drugs. Its ability to interact with biopolymers and macromolecules makes it a promising candidate for the design of novel therapeutic agents.
Used in Cosmetics:
N-(b-Hydroxytrimethylen)morpholinium chloride is also utilized in the cosmetics industry as an ingredient in various formulations. Its cationic nature allows it to interact with anionic components, providing improved stability and performance in cosmetic products.
Used in Agrochemicals:
In the agrochemical sector, N-(b-Hydroxytrimethylen)morpholinium chloride is employed as a component in the development of new pesticides and herbicides. Its ability to form complexes with target molecules can enhance the effectiveness of these products, leading to improved agricultural outcomes.
Used in Material Science:
N-(b-Hydroxytrimethylen)morpholinium chloride is used as a component in the development of advanced materials, such as polymers and coatings. Its unique structure and reactivity contribute to the creation of materials with enhanced properties, such as improved durability and functionality.
Synthesis Reference(s)
The Journal of Organic Chemistry, 46, p. 4103, 1981 DOI: 10.1021/jo00333a046
Check Digit Verification of cas no
The CAS Registry Mumber 529-00-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 529-00:
(5*5)+(4*2)+(3*9)+(2*0)+(1*0)=60
60 % 10 = 0
So 529-00-0 is a valid CAS Registry Number.
529-00-0Relevant articles and documents
Chemoenzymatic Synthesis of the Intermediates in the Peppermint Monoterpenoid Biosynthetic Pathway
Cheallaigh, Aisling Ní,Mansell, David J.,Toogood, Helen S.,Tait, Shirley,Lygidakis, Antonios,Scrutton, Nigel S.,Gardiner, John M.
, p. 1546 - 1552 (2018/08/04)
A chemoenzymatic approach providing access to all four intermediates in the peppermint biosynthetic pathway between limonene and menthone/isomenthone, including noncommercially available intermediates (-)-trans-isopiperitenol (2), (-)-isopiperitenone (3), and (+)-cis-isopulegone (4), is described. Oxidation of (+)-isopulegol (13) followed by enolate selenation and oxidative elimination steps provides (-)-isopiperitenone (3). A chemical reduction and separation route from (3) provides both native (-)-trans-isopiperitenol (2) and isomer (-)-cis-isopiperitenol (18), while enzymatic conjugate reduction of (-)-isopiperitenone (3) with IPR [(-)-isopiperitenone reductase)] provides (+)-cis-isopulegone (4). This undergoes facile base-mediated chemical epimerization to (+)-pulegone (5), which is subsequently shown to be a substrate for NtDBR (Nicotiana tabacum double-bond reductase) to afford (-)-menthone (7) and (+)-isomenthone (8).
Large-Scale Preparation of Pure (+)-(1S,2R,5S)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanol
Buschmann, Helmut,Scharf, Hans-Dieter
, p. 827 - 830 (2007/10/02)
A procedure is described for the preparation of (S)-(-)pulegone, (-)-1, starting from (S)-(-)citronellol, (-)-6, in a preparative scale.Compound (-)-1 can easily be converted into (+)-(1S,2R,5S)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexanol: (+)-2 by a procedure described in literature, which was simplified essentially.Now (+)-2 is accessible in larger amounts and thus is available as an efficient chiral auxiliary in stoichiometric asymmetric syntheses.
