529-70-4

Basic information

• Product Name: 1-(7-Hydroxy-5-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethanone
• Synonyms: 1-(7-Hydroxy-5-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethanone;1-(7-Hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)ethanone;Evodionol
• CAS NO: 529-70-4
• Molecular Formula: C₁₄H₁₆O₄
• Molecular Weight: 248.27
• Mol File: 529-70-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 416.5°Cat760mmHg
• Flash Point: 157.4°C
• Appearance: /
• Density: 1.165g/cm³
• Vapor Pressure: 1.57E-07mmHg at 25°C
• Refractive Index: 1.547
• CAS DataBase Reference: 1-(7-Hydroxy-5-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(7-Hydroxy-5-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethanone(529-70-4)
• EPA Substance Registry System: 1-(7-Hydroxy-5-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethanone(529-70-4)

Safety Data

• Hazardous Substances Data: 529-70-4(Hazardous Substances Data)

Usage

Type

Chemical compound

Classification

Coumarin derivative

Natural Occurrence

Found in various plant sources

Anti-inflammatory

Inhibits pro-inflammatory mediators

Antioxidant

Reduces oxidative stress in the body

Anti-cancer

Induces apoptosis and inhibits cancer cell growth

Health conditions

Shows promise for various health conditions

Pharmacological applications

Of interest to researchers for its potential applications

Research Focus

Investigated for its potential in cancer treatment and other health-related areas

InChI:InChI=1/C14H16O4/c1-8(15)12-10(16)7-11-9(13(12)17-4)5-6-14(2,3)18-11/h5-7,16H,1-4H3

Upstream product

• 27364-64-3 1-[4,6-dihydroxy-2-methoxy-3-(3-methylbut-2-enyl)-phenyl]ethanone 
• 27364-68-7 6-Acetyl-3,4-dihydro-7-hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran 
• 82538-75-8 2-hydroxy-3-iodo-4-O-(1,1-dimethylpropargyl)-6-methoxy-acetophenone 
• 171021-70-8 6-acetyl-5-methoxy-2,2-dimethyl-7-tosyloxy-2H-chromene 
• 541-47-9 3-Methylbutenoic acid 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 124360-56-1 6-acetyl-5,7-dihydroxy-2,2-dimethyl-4-chromanone 
• 124360-57-2 6-acetyl-5-hydroxy-2,2-dimethyl-7-tosyloxy-4-chromanone 
• 124360-58-3 6-acetyl-5-methoxy-2,2-dimethyl-7-tosyloxy-4-chromanone 
• 171021-69-5 6-acetyl-5-methoxy-2,2-dimethyl-7-tosyloxychroman-4-ol 
• 115-18-4 2-methyl-3-buten-2-ol 
• 74047-32-8 2,4-dihydroxy-3-iodo-6-methoxyphenyl methyl ketone 
• 82538-76-9 2,4-dihydroxy-5-prenyl-3-iodo-6-methoxy-acetophenone 
• 3602-54-8 4,6-dihydroxy-2-methoxyacetophenone 

Downstream Products

• 65463-74-3 oaxacacin 
• 27364-68-7 6-Acetyl-3,4-dihydro-7-hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran 
• 128031-08-3 1,3-dioxo-1-(7-hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4'-methoxyphenyl)-propane 
• 128031-09-4 1,3-dioxo-1-(7-hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(3',4'-dimethoxyphenyl)-propane 
• 5307-59-5 robustic acid 
• 22044-61-7 robustin 
• 61828-61-3 2,2-dimethyl-5-methoxy-8-(4'-methoxyphenyl)-2H,6H<1,2-b:5,4-b'>dipyran-6-one 
• 128031-11-8 2,2-dimethyl-5-methoxy-8-(3',4'-dimethoxyphenyl)-2H,6H-<1,2-b:5,4-b'>dipyran-6-one 

Relevant articles and documents

1-PHENYLETHANONE FROM ACRONYCHIA PEDUNCULATA ROOT BARK

A new arylketone, 1-phenylethanone, was isolated together with acronylin, acrovestone, bergapten, β-amyrin and three furoquinoline alkaloids from the root bark of Acronychia pedunculata. - Keywords: Acronychia pedunculata; Rutaceae; arylketone; 1-phenylethanone; furoquinoline alkaloids; acronylin; acrovestone; bergapten.

AN ELEGANT SYNTHESIS OF SOME NATURALLY OCCURRING LINEAR ACETYLCHROMENES: EUPATORIOCHROMENE, METHYLEUPATORIOCHROMENE (ENCECALIN); EVODIONOL AND METHYLEVODIONOL

An elegant synthesis of linear acetylchromenes, viz eupatoriochromene, methyleupatoriochromene (encecalin), evodionol and methylevodionol, has been achieved by blocking the reactive position C-3 of the appropriate ketones with an iodo group, prenylation with 3-chloro-3-methylbut-1-yne and subsequent cyclisation.Regiospecific introduction of C-prenyl group in the less reactive position C-5 has been achieved by the reaction of the appropriate 3-iodo ketones with 2-methylbut-3-en-2-ol.The 5-prenyl ketones are also essential intermediates for the synthesis of linear acetylchromenes.