529-96-4 Usage
Description
PYRIDOXAMINE-5'-PHOSPHATE, also known as a vitamin B6 phosphate, is a water-soluble vitamin derivative that plays a significant role in various biological processes. It is a phosphoric ester derivative of pyridoxamine, which is a part of the vitamin B6 family. PYRIDOXAMINE-5'-PHOSPHATE contains a core pyridine ring with an amino methyl group at the 4' position. PYRIDOXAMINE-5'-PHOSPHATE is naturally found in rat liver and serves as a chromophore in the biosynthesis of deoxysugars, such as 2-Deoxy-2-chloro-D-glucose (D232570).
Uses
Used in Pharmaceutical Industry:
PYRIDOXAMINE-5'-PHOSPHATE is used as a crucial component in the biosynthesis of deoxysugars for its role in various pharmaceutical applications. PYRIDOXAMINE-5'-PHOSPHATE plays a vital role in the production of 2-Deoxy-2-chloro-D-glucose (D232570), which has potential applications in the development of drugs targeting cancer and other diseases.
Used in Nutritional Supplements:
As a derivative of vitamin B6, PYRIDOXAMINE-5'-PHOSPHATE is used as a nutritional supplement to support overall health and well-being. Vitamin B6 is essential for various bodily functions, including the production of neurotransmitters, immune system support, and maintaining a healthy nervous system.
Used in Research and Development:
PYRIDOXAMINE-5'-PHOSPHATE is utilized as a research tool in the study of vitamin B6 metabolism, enzyme function, and its role in various biological processes. PYRIDOXAMINE-5'-PHOSPHATE helps researchers understand the mechanisms underlying the action of vitamin B6 and its derivatives, leading to the development of new therapeutic strategies and applications in medicine.
Biochem/physiol Actions
pK of pyridoxamine-5′-phosphate (pyridoxamine 5-phosphate, PAMP) in the singlet excited state has been evaluated by absorption and fluorescence spectral studies.
Check Digit Verification of cas no
The CAS Registry Mumber 529-96-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 529-96:
(5*5)+(4*2)+(3*9)+(2*9)+(1*6)=84
84 % 10 = 4
So 529-96-4 is a valid CAS Registry Number.
529-96-4Relevant articles and documents
Production of pyridoxal phosphate by a mutant strain of Schizosaccharomyces pombe.
Chumnantana,Hirose,Baba,Yagi
, p. 1789 - 1795 (2001)
Conditions for extracellular production of vitamin B6 compounds (B6), especially pyridoxal 5'-phosphate (PLP) by Schizosaccharomyces pombe leul strain were examined. The productivity was dependent on concentration of L-leucine in the culture medium: 30 mg/l gave the highest concentrations of total B6 and PLP. The viable cells harvested at different growth phases showed different productivity: middle and late exponential phase cells showed the highest productivity of total B6 and PLP, respectively. D-Glucose (1%, w/v) among other sugars gave the best productivity. Supplementation of air and ammonium sulfate significantly increased extracellular production of PLP. Superoxide anion producers, menadione and plumbagin, and H202 increased the productivity of PLP. Cycloheximide inhibited the increase of PLP by the oxidative stress and, in contrast, increased pyridoxine.
-
Peterson et al.
, p. 570 (1952)
-
-
Viscontini et al.
, p. 2198,2201 (1951)
-
Chemical transformations of pyridoxal and pyridoxal 5′-phosphate condensation products with amino acids
Pishchugin,Tuleberdiev
, p. 1225 - 1229 (2008/12/22)
The mechanism of chemical transformations of pyridoxal and pyridoxal 5′-phosphate condensation products with amino acids is studied by kinetic measurements. The Schiff bases are shown to be fairly stable in neutral media. In acid media, the Schiff bases a
