52908-82-4Relevant articles and documents
C-H oxygenation at tertiary carbon centers using iodine oxidant
Kiyokawa, Kensuke,Ito, Ryo,Takemoto, Kenta,Minakata, Satoshi
supporting information, p. 7609 - 7612 (2018/07/15)
An oxidation system in which iodic acid (HIO3) is used as an oxidant in the presence of N-hydroxyphthalimide (NHPI) permitted the selective hydroxylation of tertiary C-H bonds and the lactonization of carboxylic acids containing a tertiary carbon center. These reactions are operationally simple and proceed under metal-free conditions using commercially available reagents, thus offering an ideal tool for the efficient oxidation of C-H bonds at tertiary carbon centers.
Electroreductive hydrocoupling of activated olefins with ketones or aldehydes in the presence of trimethylchlorosilane
Shono, Tatsuya,Ohmizu, Hiroshi,Kawakami, Souta,Sugiyama, Hiroshi
, p. 5029 - 5032 (2007/10/02)
Electroreductive crossed hydrocoupling of α,β-unsaturated esters with aldehydes or ketones in the presence of trimethylchlorosilane afforded γ-lactones in good yields. Similarly, α,β-unsaturated nitriles gave γ-hydroxynitriles in high yields.