52943-89-2 Usage
Description
1-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)pyridinium, also known as neutral red, is a heterocyclic compound that features both a pyridine and a purine ring. It is widely recognized for its applications in histology and cell biology as a stain for living and fixed cells, allowing for the visualization of lysosomes within cells. Its unique properties have also made it a subject of interest for potential therapeutic uses, including photodynamic therapy for cancer treatment, neuroprotection, and as an anti-inflammatory agent.
Uses
Used in Histology and Cell Biology:
1-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)pyridinium is used as a staining agent for [application reason] to visualize the structure and function of living and fixed cells, particularly focusing on lysosomes.
Used in Photodynamic Therapy for Cancer Treatment:
In the field of oncology, 1-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)pyridinium is used as a potential therapeutic agent for [application reason] its ability to accumulate in lysosomes, which may aid in the selective targeting of cancer cells and enhance the effectiveness of photodynamic therapy.
Used in Neuroprotection:
1-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)pyridinium is used as a neuroprotective agent for [application reason] its potential to shield neurons from damage and promote the survival of nerve cells, which could be beneficial in treating neurodegenerative diseases.
Used as an Anti-inflammatory Agent:
Within the realm of inflammation and immune response, 1-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)pyridinium is used as an anti-inflammatory agent for [application reason] its possible role in reducing inflammation and modulating immune responses, which could be applicable in treating various inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 52943-89-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,9,4 and 3 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 52943-89:
(7*5)+(6*2)+(5*9)+(4*4)+(3*3)+(2*8)+(1*9)=142
142 % 10 = 2
So 52943-89-2 is a valid CAS Registry Number.
52943-89-2Relevant articles and documents
Substitution of Bromine Atom in 8-Bromotheophylline by Pyridine in the Presence of o-Phenylenephosphoric Acid Isocyanate
Bobkov, V. N.,Zvolinskaya, T. V.,Kuz'menko, I. I.
, p. 825 (1988)
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REACTION OF 8-BROMOTHEOPHYLLINE WITH PYRIDINE AND ALKYLPYRIDINES. 8-PYRIDINIOTHEOPHYLLINATES
Bobkov, V. N.,Zvolinskaya, T. V.,Kuz'menko, I. I.
, p. 1285 - 1288 (2007/10/02)
The reaction of 8-bromotheophylline with pyridine or alkylpyridines in the presence of electrophilic reagents proceeds with the formation of 8-pyridiniotheophyllinates.The possible mechanism of the reaction is discussed.
