52951-14-1 Usage
General Description
1-Methyl-1H-indole-7-carbonitrile is a chemical compound with the molecular formula C10H8N2. It is primarily categorized under the indoles chemical group, which contains a phenyl group fused to a pyrrole ring. As a derivative of indole, this compound shares many chemical properties with its parent compound, including aromaticity and the ability to participate in various chemical reactions. Its carbonitrile group gives it increased reactivity and potential for further functionalization. This chemical is used in various areas of chemical research and it's relevant in the pharmaceutical industry for drug synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 52951-14-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,9,5 and 1 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 52951-14:
(7*5)+(6*2)+(5*9)+(4*5)+(3*1)+(2*1)+(1*4)=121
121 % 10 = 1
So 52951-14-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N2/c1-12-6-5-8-3-2-4-9(7-11)10(8)12/h2-6H,1H3
52951-14-1Relevant articles and documents
Photocatalytic Alkylation of Pyrroles and Indoles with α-Diazo Esters
Ciszewski, Lukasz W.,Durka, Jakub,Gryko, Dorota
supporting information, p. 7028 - 7032 (2019/09/12)
This article describes the photoalkylation of electron-rich aromatic compounds with diazo esters. C-2-alkylated indoles and pyrroles are obtained with good yields even though the photocatalyst loading is as low as 0.075 mol %. For EWG-substituted substrates, the addition of a catalytic amount of N,N-dimethyl-4-methoxyaniline is required. Both EWG-EWG- and EWG-EDG-substituted diazo esters are suitable as alkylating agents. The reaction selectivity and mechanistic experiments suggest that carbenes/carbenoid intermediates are not involved in the reaction pathway.
