52955-49-4

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-[2-(methylphenylamino)ethyl]-
• CAS NO: 52955-49-4
• Molecular Formula: C17H16N2O2
• Molecular Weight: 280.326
• Mol File: 52955-49-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-[2-(methylphenylamino)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-[2-(methylphenylamino)ethyl]-(52955-49-4)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-[2-(methylphenylamino)ethyl]-(52955-49-4)

Safety Data

• Hazardous Substances Data: 52955-49-4(Hazardous Substances Data)

Upstream product

• 574-98-1 2-(2-bromoethyl)isoindoline-1,3-dione 
• 121-69-7 N,N-dimethyl-aniline 
• 100-61-8 N-methylaniline 
• 51905-47-6 N-Methyl,N-{(2-bromo)-1-ethyl}aniline 
• 1074-82-4 potassium phtalimide 

Downstream Products

• 82583-89-9 2-Phenyl-3,4-dihydro-2H-pyrazino[2,1-a]isoindol-6-one 
• 1664-39-7 N-methyl-N-phenylethylenediamine 
• 65325-40-8 10b-hydroxy-2-phenyl-1,3,4,10b-tetrahydro-2H-pyrazino[2,1-a]isoindol-6-one 

Relevant articles and documents

METHODS AND COMPOSITIONS FOR DETECTING OR MEASURING CASPASES OR APOPTOSIS

Provided herein are compounds, enzyme substrates, compositions, kits, uses, and methods for detecting the presence or absence of a caspase enzyme, measuring the activity of a caspase enzyme, or detecting the presence or absence of apoptosis. The detection or measurement can occur through intracellular cleavage of a compound or enzyme substrate, which can lead to an increase in fluorescence, e.g., in the violet or red channel, through liberation of a nucleic acid binding dye from a peptide, such as liberation of a DNA-binding dye from a negatively charged peptide comprising a sequence recognized and cleaved by a caspase