52982-90-8 Usage
Chemical compound
2-Amino-6-chloro-4-methyl-nicotinonitrile
Class
Nitriles
Functional groups
Amino group, chloro group, methyl group
Appearance
White to light yellow crystalline powder
Uses
Intermediate in the synthesis of pharmaceuticals, pesticides, and other organic compounds; production of agrochemicals; building block in the preparation of heterocyclic compounds
Potential applications
Research and development of new drugs
Caution
Properties, hazards, and safety measures should be carefully evaluated before use
Check Digit Verification of cas no
The CAS Registry Mumber 52982-90-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,9,8 and 2 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 52982-90:
(7*5)+(6*2)+(5*9)+(4*8)+(3*2)+(2*9)+(1*0)=148
148 % 10 = 8
So 52982-90-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H6ClN3/c1-4-2-6(8)11-7(10)5(4)3-9/h2H,1H3,(H2,10,11)
52982-90-8Relevant articles and documents
NEW TRPA1 ANTAGONISTS
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Page/Page column 46; 47, (2017/05/02)
The present invention relates to bicyclic heterocyclic derivatives of Forrmula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by TRPA1 channel inhibition or antagonism.
Synthesis and Reactivity of 2,6-Diamino-4-methyl-3-pyridinecarbonitrile
Katritzky, Alan R.,Rachwal, Stanislaw,Smith, Terrance P.,Steel, Peter J.
, p. 979 - 984 (2007/10/02)
2,6-Dihydroxy-4-methyl-3-pyridinecarbonitrile is converted via its 2,6-dichloro analog into the corresponding 2-amino-6-chloro, 2-chloro-6-amino, and 2,6-diamino derivatives.The last reacts with benzenesulfonyl chloride to yield a tris-sulfonyl derivative, the structure of which is demonstrated by X-ray analysis.
