53009-06-6

Basic information

• Product Name: 2,3,11,12-tetramethoxy-4b,5,9,13b,15,16-hexahydro-8H-pyrimido[2,1-a;4,3-a']diisoquinoline-6-one
• Synonyms: 2,3,11,12-tetramethoxy-4b,5,9,13b,15,16-hexahydro-8H-pyrimido[2,1-a;4,3-a']diisoquinoline-6-one
• CAS NO: 53009-06-6
• Molecular Weight: 424.497
• Mol File: 53009-06-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3,11,12-tetramethoxy-4b,5,9,13b,15,16-hexahydro-8H-pyrimido[2,1-a;4,3-a']diisoquinoline-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,11,12-tetramethoxy-4b,5,9,13b,15,16-hexahydro-8H-pyrimido[2,1-a;4,3-a']diisoquinoline-6-one(53009-06-6)
• EPA Substance Registry System: 2,3,11,12-tetramethoxy-4b,5,9,13b,15,16-hexahydro-8H-pyrimido[2,1-a;4,3-a']diisoquinoline-6-one(53009-06-6)

Safety Data

• Hazardous Substances Data: 53009-06-6(Hazardous Substances Data)

Upstream product

• 5693-62-9 2,3,4,5-tetrahydro-6-methoxypyridine 
• 14028-68-3 ethyl 2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)acetate 

Relevant articles and documents

Synthesis and stereochemistry of 8,13-diaza-2,3-dimethoxygona-1,3,5(10),9(11)-tetraen-12-one and D-homo derivatives

From the condensation reaction of O-methylbutyrolactim (2), O-methylvalerolactim (3), O-methylcaprolactim (4) and O-methyl-4-t-butylcaprolactim (5) with ethyl 6,7-dimethoxy-α-acetate (1), 8,13-diaza-2,3-dimethoxygona-1,3,5(10),9(11)-tetraen-12-one (6) D-homo-derivatives (7-9), and medium sized ring cyclic diamides (10,11) were obtained.The stereoselective reduction of compounds 6-9 by Adam's platinum catalyst afforded 8,13-diaza-2,3-dimethoxygona-1,3,5(10)-trien-12-one (12) and its D-homo derivatives (13-15).The structures of thecompounds obtained were established by NMR and X-ray crystallographic analyses. - Keywords: 8,13-diazasteroids; stereochemistry; X-ray structure analysis