53013-41-5Relevant articles and documents
Discovery of novel FMS kinase inhibitors as anti-inflammatory agents
Illig, Carl R.,Chen, Jinsheng,Wall, Mark J.,Wilson, Kenneth J.,Ballentine, Shelley K.,Rudolph, M. Jonathan,DesJarlais, Renee L.,Chen, Yanmin,Schubert, Carsten,Petrounia, Ioanna,Crysler, Carl S.,Molloy, Christopher J.,Chaikin, Margery A.,Manthey, Carl L.,Player, Mark R.,Tomczuk, Bruce E.,Meegalla, Sanath K.
, p. 1642 - 1648 (2008/12/22)
The optimization of the arylamide lead 2 resulted in identification of a highly potent series of 2,4-disubstituted arylamides. Compound 8 (FMS kinase IC50 = 0.0008 μM) served as a proof-of-concept candidate in a collagen-induced model of arthri
Regular trends in nucleophilic substitutions in 2-alkylamino-4- chloronitrobenzenes
Zotova,Kushakova,Kuznetsov,Rodin,Garabadzhiu
, p. 214 - 217 (2007/10/03)
The effect of substituents in position 2 on the reactivity of 2-alkylamino-4-chloronitrobenzenes in nucleophilic substitution by N-nucleophiles of various character was studied. 2005 Pleiades Publishing, Inc.