530135-29-6Relevant articles and documents
Novel Hepatitis C virus replicon inhibitors: Synthesis and structure-activity relationships of fused pyrimidine derivatives
Chris Krueger,Madigan, Darold L.,Beno, David W.,Betebenner, David A.,Carrick, Robert,Green, Brian E.,He, Wenping,Liu, Dachun,Maring, Clarence J.,McDaniel, Keith F.,Mo, Hongmei,Molla, Akhteruzzaman,Motter, Christopher E.,Pilot-Matias, Tami J.,Tufano, Michael D.,Kempf, Dale J.
scheme or table, p. 2212 - 2215 (2012/04/18)
The synthesis of several pyrido[2,3-d]pyrimidine and pyrimido[4,5-d] pyrimidine analogs is described with one such analog possessing subnanomolar potency in both genotype 1a and 1b cell culture HCV replicon assays.
Nitrophenyl derivatives as aldose reductase inhibitors
Costantino, Luca,Ferrari, Anna Maria,Gamberini, Maria Cristina,Rastelli, Giulio
, p. 3923 - 3931 (2007/10/03)
Nitrophenyl derivatives were recently discovered as a new class of ALR2 inhibitors by means of docking and database screening of the National Cancer Institute database of organic molecules. The nitro group was predicted to bind to the Tyr48 and His110 act