53044-18-1

Basic information

• Product Name: 2,6-Dichloro-N,N-dimethylbenzamide
• Synonyms: 2,6-Dichloro-N,N-dimethylbenzamide
• CAS NO: 53044-18-1
• Molecular Formula: C₉H₉Cl₂NO
• Molecular Weight: 218.0799
• Mol File: 53044-18-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 345.7°Cat760mmHg
• Flash Point: 162.9°C
• Appearance: /
• Density: 1.293g/cm³
• Vapor Pressure: 6.03E-05mmHg at 25°C
• Refractive Index: 1.558
• CAS DataBase Reference: 2,6-Dichloro-N,N-dimethylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dichloro-N,N-dimethylbenzamide(53044-18-1)
• EPA Substance Registry System: 2,6-Dichloro-N,N-dimethylbenzamide(53044-18-1)

Safety Data

• Hazardous Substances Data: 53044-18-1(Hazardous Substances Data)

Usage

General Description

2,6-Dichloro-N,N-dimethylbenzamide, also known as DCDM, is a chemical compound that belongs to the benzamide family. It is a white crystalline solid that is insoluble in water but soluble in organic solvents. DCDM is primarily used as a herbicide to control grasses and broadleaf weeds in various crops such as soybeans, corn, and peanuts. It works by inhibiting the synthesis of chlorophyll, ultimately leading to the death of the targeted plants. However, DCDM has been linked to potential environmental and human health concerns, as it has been found to persist in soil and water and may have toxic effects on aquatic organisms. As a result, its use has been heavily regulated in some regions.

InChI:InChI=1/C9H9Cl2NO/c1-12(2)9(13)8-6(10)4-3-5-7(8)11/h3-5H,1-2H3

Upstream product

• 83-38-5 2,6-dichlorobenzaldehyde 
• 68-12-2 N,N-dimethyl-formamide 

Relevant articles and documents

Oxidative amidation of benzaldehydes and benzylamines with: N -substituted formamides over a Co/Al hydrotalcite-derived catalyst

The present work describes a highly efficient synthetic strategy for amides via oxidative coupling of benzaldehydes or benzylamines with N-substituted formamides using a heterogeneous Co/Al hydrotalcite-derived catalyst in the presence of TBHP. A series of Co/Al hydrotalcite-derived catalysts (Cat-2, Cat-3, and Cat-4 with the Co2+/Al3+ molar ratio in the synthesis mixture as 1/1, 2/1 and 3/1) have been prepared by a simple co-precipitation method and characterized using powder XRD, XPS, FEG-SEM, EDS, FT-IR, DTG-TGA and N2 physical adsorption techniques. Among the as-prepared catalysts, Cat-3 exhibited excellent catalytic activity towards the direct amidation of benzaldehydes as well as benzylamines bearing various substituents into the corresponding amides at 100 °C using TBHP as an oxidant. The mechanistic investigation of the amidation reaction revealed that the reaction follows a radical pathway. Furthermore, the catalyst is easily separable and recyclable without considerable loss in catalytic activity.