53081-61-1

Basic information

• Product Name: (E)-1-(but-1-en-3-yn-1-yl)-4-chlorobenzene
• Synonyms: (E)-1-(but-1-en-3-yn-1-yl)-4-chlorobenzene
• CAS NO: 53081-61-1
• Molecular Weight: 162.619
• Mol File: 53081-61-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (E)-1-(but-1-en-3-yn-1-yl)-4-chlorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(but-1-en-3-yn-1-yl)-4-chlorobenzene(53081-61-1)
• EPA Substance Registry System: (E)-1-(but-1-en-3-yn-1-yl)-4-chlorobenzene(53081-61-1)

Safety Data

• Hazardous Substances Data: 53081-61-1(Hazardous Substances Data)

Upstream product

• 1346459-93-5 (E)-4-(4-chlorophenyl)-1-(trimethylsilyl)but-3-en-1-yne 
• 66482-29-9 1-[(E)-2-bromoethenyl]-4-chlorobenzene 
• 77295-59-1 1-chloro-4-(2,2-dibromovinyl)benzene 
• 1620635-60-0 (E)-1-chloro-4-(4,4-dibromobuta-1,3-dienyl)benzene 
• 1075-77-0 (E)-4-chlorocinnamic aldehyde 
• 66482-29-9 1-(2-bromovinyl)-4-chlorobenzene 
• 1612145-82-0 C₁₃H₁₃ClO 
• 104-88-1 4-chlorobenzaldehyde 
• 24583-70-8 (E)-3-(p-chlorophenyl)prop-2-en-1-ol 
• 56506-90-2 (dibromomethyl)(triphenyl)phosphonium bromide 
• 24393-52-0 ethyl (E)-3-(4-chlorophenyl)prop-2-enoate 
• 42249-99-0 1-(4-chlorophenyl)but-3-yn-1-ol 

Downstream Products

• 87623-79-8 5-(4-chlorophenyl)-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazole 
• 104-88-1 4-chlorobenzaldehyde 
• 1562381-49-0 (E)-N-(4-(4-chlorophenyl)but-3-en-1-yn-1-yl)-N,4-dimethylbenzenesulfonamide 
• 1562381-59-2 4-(4-chlorophenyl)-4-hydroxy-N-methyl-N'-phenyl-N-tosylbut-2-ynimidamide 
• 1612145-46-6 (R,E)-6-(4-chlorophenyl)-2-phenylhex-5-en-3-yn-2-ol 
• 49678-03-7 (2E,4E)-5-(4'-chlorophenyl)-2,4-pentadienol 
• 40642-91-9 (E)-4-(4-chlorophenyl)-1-phenylbut-3-en-2-one 
• 1234862-83-9 (3E)-4-(4-chlorophenyl)-1-phenylbut-3-en-1-one 
• 53176-54-8 (E,Z)-6-(p-Chlorphenyl)-3,5-hexandien-1-ol 
• 53081-70-2 5-(p-Chlorphenyl)-1,3-cyclohexadien 
• 53081-65-5 (E,Z)-1-(p-Chlorophenyl)-1,3,5-hextrien 
• 53081-62-2 (E)-6-(4-Chlor-phenyl)-5-hexen-3-in-1-ol 

Relevant articles and documents

Gold(I)-Catalyzed Oxidative 1,4-Additions of 3-En-1-ynamide with Nitrones via Carbon- versus Nitrogen-Addition Chemoselectivity

This work reports gold-catalyzed 1,4-oxofunctionalizations of 3-en-1-ynamides with nitrones, yielding two distinct E-configured products. We obtained 1,4-oxoarylation products from 3-en-1-ynamides bearing C(4)-electron-donating substituents and 1,4-oxoamination products from those analogues bearing C(4)-aryl substituents. We propose that if vinylgold carbenes are stable, imines undergo a para-arylation on these gold carbenes. If vinylgold carbenes are highly electron-deficient, this N-attack is irreversible to enable 1,4-oxoaminations.

Regioselective hydrations of 1-aryl-3-en-1-ynes using gold and platinum catalysts: Selective production of 2-en-1-ones and 3-en-1-ones

Regiocontrolled hydrations of 1-aryl-3-en-1-ynes have been accomplished with IPrAuOTf and PtCl2/CO to yield 3-en-1-ones and 2-en-1-ones efficiently; our experimental data indicates that the sizes of catalysts play an important role. This journa

Synthesis of 1,3,5-trisubstituted pyrazolines via Zn(ii)-catalyzed double hydroamination of enynes with aryl hydrazines

An efficient Zn(ii)-catalyzed intermolecular double hydroamination of 1,3-enynes with aryl hydrazines, for the synthesis of pyrazolines, has been discussed.